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Lab: Staining

Terms

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Wright Stain  
  • Romanowsky type
  • Primary ingredients:
    • methylene blue (neg, basic dye)
    • eosin Y or eosin B (pos, acid dye)
    • methyl alcohol
    • phosphate buffer pH 6.4-6.7
  • P
Wright Stain Procedure
  1. Prepare smear & air dry
  2. Fix smear in methyl alcohol (adhere cells to slide, down't wash off & holds morphology)
  3. Add methylene blue/eosin stain for 3 min
  4. Add phosphte buffer to stain and mix<
Reticulocyte Stain
  • Supravital stain (added to cell when still living before putting on slide)
  • Primary ingredients
    • new methylene blue or brillant cresyl blue
    • NaCl
  • Primary reaction:
Fetal Hemoglobin Stain
  • aka Acid Elution test for Hgb F
  • Primary ingredients:
    • citric acid-phosphate buffer
    • acid hematoxylin
    • erythrosin (dye counter stain)
  • Primary reaction:
Iron Stain
  • aka Prussian Blue reaction
  • Primary ingredients:
    • 2% potassium ferrocyanide
    • 2% HCL
  • Primary reaction:
    • Fe3+ + K3+ ferrocyanide = ferric ferrocyanid
Heinz Body Stain    
  • Supravital stain
  • Primary ingredients:
    • crystal violet or methyl violet solution
  • Primary reaction: staining of denatured and precipitated hemoglobin

Deck Info

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