Virology Exam II
Terms
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- Type of Genome for Parvoviridae
- very stable ssDNA
-
Type of Genome for Papovaviridae
(warts) -
stable dsDNA
episome (no provirus) - Type of Genome for Adenoviridae
- dsDNA
- Type of Genome for Poxviridae
- Stable and independent dsDNA
- Type of Genome for Herpesviridae
-
dsDNA
episome or provirus - Type of Genome for Asfarviridae
- Heat labile dsDNA
- Type of Genome for Retroviridae
-
ssRNA
provirus and episome - Type of Genome for Rhabdoviridae
- ssRNA
- Type of Genome for Orthomyxoviridae
- labile Segmented ssRNA
- Is Parvoviridae Enveloped?
- No
- Is Papovaviridae Enveloped?
- No
- Is Adenoviridae Enveloped?
- No
- Is Poxviridae Enveloped?
- Yes and No
- Is Herpesviridae Enveloped?
- Yes
- Is Asfarviridae Enveloped?
- Yes
- Is Retroviridae Enveloped?
- Yes
- Is Rhabdoviridae Enveloped?
- Yes
- Is Orthomyxoviridae Enveloped?
- Yes
- What is the capsid morphology of Parvoviridae?
- Icosahedral
- What is the capsid morphology of Papovaviridae?
- Icosahedral
- What is the capsid morphology of Adenoviridae?
- Icosahedral
- What is the capsid morphology of Poxviridae?
- Complex and non-Symmetrical (brick shaped or ovoid virion)
- What is the capsid morphology of Herpesviridae?
- Icosahedral (pleomorphic virion)
- What is the capsid morphology of Asfarviridae?
- Icosahedral (spherical virion)
- What is the capsid morphology of Retroviridae?
- Spherical to rod shaped helical (spherical virion)
- What is the capsid morphology of Rhabdoviridae?
- Helical (bullet shaped virion)
- What is the capsid morphology of Orthomyxoviridae?
- Helical (Spherical or filamentous virion)
- What is the size of Parvoviridae?
- Small
- What is the size of Papovaviridae?
- Small
- What is the size of Adenoviridae?
- Medium
- What is the size of Poxviridae?
- Extra Large (largest)
- What is the size of Herpesviridae?
- Large
- What is the size of Asfarviridae?
- Extra Large
- What is the size of Retroviridae?
- Medium
- What is the size of Rhabdoviridae?
- Medium
- What is the size of Orthomyxoviridae?
- Medium
- How does Parvoviridae enter the cell?
- R-M Endocytosis
- How does Papovaviridae enter the cell?
- R-M Endocytosis
- How does Adenoviridae enter the cell?
- Fiber-cell receptor attachment or endocytosis
- How does Poxviridae enter the cell?
- Fusion or R-M Endocytosis
- How does Herpesviridae enter the cell?
- Fusion or R-M Endocytosis
- How does Asfarviridae enter the cell?
- R-M Endocytosis
- How does Retroviridae enter the cell?
- R-M Endocytosis
- How does Rhabdoviridae enter the cell?
- Fusion or R-M Endocytosis
- How does Orthomyxoviridae enter the cell?
- R-M Endocytosis
- Where does Parvoviridae replicate in the cell?
- Nucleus
- Where does Papovaviridae replicate in the cell?
- Nucleus
- Where does Adenoviridae replicate in the cell?
- Nucleus
- Where does Poxviridae replicate in the cell?
- Cytoplasm
- Where does Herpesviridae replicate in the cell?
- Nucleus
- Where does Asfarviridae replicate in the cell?
- Cytoplasm
- Where does Retroviridae replicate in the cell?
- Nucleus and Cytoplasm
- Where does Rhabdoviridae replicate in the cell?
- Cytoplasm
- Where does Orthomyxoviridae replicate in the cell?
- Nucleus (eclipse) and Cytoplasm (maturation)
- What kind of inclusion bodies does Parvoviridae have?
- Nuclear
- What kind of inclusion bodies does Papovaviridae have?
- What kind of inclusion bodies does Adenoviridae have?
- Nuclear
- What kind of inclusion bodies does Poxviridae have?
- Cytoplasmic
- What kind of inclusion bodies does Herpesviridae have?
- Nuclear
- What kind of inclusion bodies does Asfarviridae have?
- Cytoplasmic
- What kind of inclusion bodies does Retroviridae have?
- What kind of inclusion bodies does Rhabdoviridae have?
- May or may not have Cytoplasmic Inclusion bodies
- What kind of inclusion bodies does Orthomyxoviridae have?
- How is Parvoviridae released from the cell?
- Cytolysis
- How is Papovaviridae released from the cell?
- Cytolysis
- How is Adenoviridae released from the cell?
- Cytolysis
- How is Poxviridae released from the cell?
- Budding from Golgi, exocytosis or cytolysis
- How is Herpesviridae released from the cell?
- Exocytosis (fusion) or cytolysis
- How is Asfarviridae released from the cell?
- Budding PM
- How is Retroviridae released from the cell?
- Budding PM
- How is Rhabdoviridae released from the cell?
- Budding PM or cytolysis (VSV is both)
- How is Orthomyxoviridae released from the cell?
- Budding PM
- What is the cell tropism for Parvoviridae?
- Cells with high mitotic rate (GI, WBC)
- What is the cell tropism for Papovaviridae?
- Surface (integument) and Mucosal (digestive, U/G) epithelium
- What is the cell tropism for Adenoviridae?
- Epithelial Cells (especially respiratory and enteric)
- What is the cell tropism for Poxviridae?
- Epithelial Cells (permissive) and macrophages (semi-permissive)
- What is the cell tropism for Herpesviridae?
- Varies with disease: Mucosal surfaces of respiratory or U/G, lymphoid tissue
- What is the cell tropism for Asfarviridae?
- Lymphoreticular tissue (especially macrophages)
- What is the cell tropism for Retroviridae?
- WBC's (Macrophages, B & T cell stems cells, lymphocytes)
- What is the cell tropism for Rhabdoviridae?
- Depends on disease: epithelium only (VSV), neurons, secretory epithelium (rabies)
- What is the cell tropism for Orthomyxoviridae?
- Respiratory Epithelium (birds and mammals), GI (birds) Sialic acid and cell restriction
- What is the incubation period for Parvoviridae?
- Short (2-10 days)
- What is the incubation period for Papovaviridae?
- Short in permissive; Long in semi or non-permissive
- What is the incubation period for Adenoviridae?
- Long (weeks)
- What is the incubation period for Poxviridae?
- Short (<7 days); Shorter than papilloma viruses
- What is the incubation period for Herpesviridae?
- Depends on Disease
- What is the incubation period for Asfarviridae?
- 5-15 days
- What is the incubation period for Retroviridae?
- not specified
- What is the incubation period for Rhabdoviridae?
- Neurons = 14-90 days; Epithelium = 1-5 days
- What is the incubation period for Orthomyxoviridae?
- Short (a few days or even 1 hour with virulent avian)
- What is the mode of transmission for Parvoviridae?
- Horizontal (O/F, fomites) and Vertical (transplacental)
- What is the mode of transmission for Papovaviridae?
- Horizontal (direct contact: skin and mucous membranes)
- What is the mode of transmission for Adenoviridae?
- Horizontal: O/F, respiratory, urine
- What is the mode of transmission for Poxviridae?
- Horizontal - direct contact (skin, respiratory-systemic, mechanical vectors)
- What is the mode of transmission for Herpesviridae?
- Horizontal (direct contact, lactogenic, blood) or vertical (transplacental)
- What is the mode of transmission for Asfarviridae?
- Horizontal (respiratory, soft tick, O/F, infected pork)
- What is the mode of transmission for Retroviridae?
- Horizontal and vertical: immune response mediated
- What is the mode of transmission for Rhabdoviridae?
- Horizontal (skin or mucosal lesions)
- What is the mode of transmission for Orthomyxoviridae?
- Horizontal (respiratory-aerosols, orofecal-birds)
- What are the main diseases caused by Parvoviridae?
- Immunosuppression, GI: FPV, CPV, PPV
- What are the main diseases caused by Papovaviridae?
- Episomes - productive or non-productive papillomas (warts, GI or U/G)
- What are the main diseases caused by Adenoviridae?
- persistently productive, subclinical to acute mild respiratory or enteric to systemic: ICH (CAV-1)
- What are the main diseases caused by Poxviridae?
- (systemic) Septicemia -> viremia -> dissem. Infection of skin and internal organs (Cowpox, Orf, Pseudocowpox, Fowlpox)
- What are the main diseases caused by Asfarviridae?
- African Swine Fever (non-neutralizing Ab's)
- What are the main diseases caused by Retroviridae?
- Persistent/Productive/Latent transformation: ALV/ASV, bovine leukemia, FIV, FeLV, FeSV, EIA, Visna/Maedi, OPP, CAEV
- What are the main diseases caused by Rhabdoviridae?
- Rabies, Vesicular stomatitis
- What are the main diseases caused by Orthomyxoviridae?
- Influenza (avian "fowl plague," swine, equine)