vascular pathology
Terms
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- Buerger's Disease Buerger's disease is also known as?
- smoker's disease, thromboangiitis obliterans
- Buerger's Disease What are the Sx (5)?
- intermittent claudication, superficial nodular phlebitis, cold sensitivity, severe pain in affected part, may lead to gangrene
- Buerger's Disease What is the Tx?
- Quit smokng
- Takayasu's arteritits Also known as ?
- pulseless disease
- Takayasu's arteritits What is it?
- thickening of aortic arch and/or proximal great vessels
- Takayasu's arteritits ESR elevated?
- yes
- Takayasu's arteritits Primarily affects whom?
- Young Asian Females
- Takayasu's arteritits Mnemomic
- FAN MY SKIN On Wednesday
- Takayasu's arteritits Sx (7)
- Fever, Arthritis, Night Sweats, Myalgia, Ocular Disturbances, Weak pulses in upper extremities
- Temporal Arteritis: Also known as?
- Giant Cell Arteritis
- Temporal Arteritis: Affects what vessels?
- medium and small arteries (usually carotid branches)
- Temporal Arteritis: ESR elevated?
- yes
- Temporal Arteritis: Primarily affects whom?
- Elderly Females
- Temporal Arteritis: Sx (3)
- Unilateral Headache
- Temporal Arteritis: Many patients are also affected with this syndrome
- Polymalgia Rheumatica
- Temporal Arteritis: Tx (?)
- Steroids
- Polyarteritis Nodosa: How would you describe the inflammation in this disease?
- necrotizing, caused by immune complex deposition
- Polyarteritis Nodosa: In which vessels?
- small to medium-sized muscular arteries, renal and visceral vessels
- Polyarteritis Nodosa: ESR elevated?
- yes
- Polyarteritis Nodosa: Sx (7) ⬦ and they are SO specific
- fever, weight loss, malaise, abdominal pain, headache, myalgia, hypertension
- Polyarteritis Nodosa: Other findings
- cotton-wool spots, microaneurysms, pericarditis, myocarditis, palpable purpura
- Polyarteritis Nodosa: What viral infection is found in 30% of PN patients?
- Hepatitis B
- Polyarteritis Nodosa: what antibody is associated with this disease?
- P-ANCA
- Polyarteritis Nodosa: What two ways can you remember that?
- P-ANCA --> PAN (PolyArteritis Nodosa), Just memorize it
- Polyarteritis Nodosa: What does P-ANCA refer to?
- Perinuclear pattern of Antineutrophil Cytoplasmic Antibodies
- Polyarteritis Nodosa: Primarily affects whom?
- Young males
- Polyarteritis Nodosa: Tx
- Corticosteroids, Azathioprine, Cyclophosphamide
- Wegener's Granulomatosis What are three major findings (hint: they are necrotizing)
- Focal Necrotizing Vasculitism, Necrotizing granulomas of the lung and upper airway, Necrotizing glomerulonephritis
- Wegener's Granulomatosis Sx (7)
- Perforated nasal septum, Chronic Sinusitis, Otitis Media, Mastoiditis, Cough, Dyspnea, Hemoptysis
- Wegener's Granulomatosis What antibody is associated with this disease
- C-ANCA
- Wegener's Granulomatosis What should you look for on CXR?
- large nodular densities
- Wegener's Granulomatosis Tx
- Corticosteroids, Azathioprine, Methotrexate
- Kawasaki Disease: Who gets it?
- infants, kids
- Kawasaki Disease: What is the disease course?
- acute, self-limiting
- Kawasaki Disease: What vessels are involved?
- small and medium sized
- Kawasaki Disease: What does CRASH stand for
- Conjunctivitis, Rash (truncal), Aneurysms of Coronary Arteries, Strawberry tongue, changes in lips/oral mucosa; Hands and Feet show induration and desquamation