vet virology
Terms
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copy deck
- define virus
- self-rreplicating nucleoprotien
- What is a viron?
- mature (complete) virus particle
- This is the smallest amount of virus/volume capable of producing the reaction being measured.
- Infectious unit
- Which kind of virus induces cytolysis when exiting the cell?
- nonenveloped
- Which phase msut a cell be in to have the components available for DNA synthesis>
- s-phase
- This is the viral encoded protein coat surrounding the core.
- capsid
- This is the capsid and its enclosed core.
- nucleocapsid
- What are the three envelope proteins?
-
peplomer
viral attatchment proteins
antigenic proteins - This is a bridge between the nucleocapsid and the internal membrane of the envelope.
- matrix protein
- what are the four possible cytopathic effects of virus?
-
cell lysis
syncytia formation
inclusion bodies
transformation - Which assay measurement is either all or none?
- quantal
- Viral genome integrated into cellular DNA
- provirus
- viral genome persists in the nucleas as an extrachromosomal element
- episome
- This is a cell that will support a productive viral infection
- permissive cell
- This is a cell that will not support a productive viral infection, an abortive infection results, cell may be transformed.
- non-permissive cell
- This plaque assay measures the actual amount of infectious units per dilution.
- quantitative assay
- This plaque assay is measured by counting lesions on CAMs of egg embryos.
- pock assay
- What are the three different plaque assays?
-
quantitative
pock
cell culture - What does a Virus-serum neutralization assay do?
- Estimates the amount of antiviral antibodies that can neutralize viral infectivity.
- This modern assay tells you viral specific antigens the body is responding to.
- Western Immunoblot
- What are the two mechanisms of penetration for a virus?
-
fushion
receptor mediated endocytosis - What two major things happen during the eclipse phase?
-
production of viral regulatory enzymes and structural proteins
replication of viral nucleic acid - What are two examples of direct viral infection of immune system effector cells?
-
lysis of lymphoreticular cells
viral-induced immune cell - z
- z