Rabies
Terms
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- what type of virus is rabies?
- ssRNA
- what is the reservoir of rabies?
- MAMMALS
- what is the most common source of rabies?
- Raccoons
- What are 4 other sources?
- Skunks, bats, foxes, dogs.
- How is rabies transmitted?
- Animal bites mostly
- What is the pathologic course of rabies infections?
-
-Incubates few weeks
-Transport to CNS
-CNS replication
-Replication further in secretory organs - How are humans diagnosied with rabies if they are still ALIVE?
-
-Serologic methods on Serum/CSF
-Skin neck biopsy for Ag
-Viral isolation from saliva - What test assess Rabies virus response to treatment?
- RT-PCR
- What is the gold standard post mortem diagnostic test for rabies?
- DFA on Brain Tissue.
- What are the characteristic inclusion bodies seen in Rabies?
- Negri bodies
- What does EM of rabies allow us to see?
- Rod-shape
- Is Rabies treatable?
- Rarely; only 3 cases survived after CNS symptoms.
- What is "treatment" for rabies?
- Vaccine; vaccine+booster for high risk occupations.