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pharm toxicology 4-26-06

Terms

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What is the antidote for acetaminophen toxicity/overdose
N-acetylcysteine
What is the antidote for salicylates toxicity/overdose
Alkanize urine/dialysis
What is the antidote for antichoinesterase toxicity/overdose
Atropine, pralidoxime
What is the antidote for antimuscarinic/anticholinergic agents toxicity/overdose
physostigimine salicylate
What is the antidote for Beta-blockers toxicity/overdose
glucagon
What is the antidote for digitalis toxicity/overdose
Stop digitalis, Normalize K+, lodpcaine, anti-digitialis Fab Fragments, Magnesium
What is the antidote for lead toxicity/overdose
CaEDTA, dimercaprol, succimer, penicillamine
What is the antidote for iron toxicity/overdose
Deferoxamine
What is the antidote for aresnic/mercury/gold toxicity/overdose
Dimercaprol (BAL), succimer
What is the antidote for copper, arsenic, gold toxicity/overdose
Penicillamine
What is the antidote N-acetylcysteine used to treat?
Acetaminophen toxicity/overdose
What is the antidote for cyanide toxicity/overdose
nitrite, hydroxocobalamin, thiosoulfate
What is the antidote for methemoglobin toxicity/overdose
methylene blue
What is the antidote glucagon used to treat?
Beta-blocker toxicity/overdose
What is the antidote for carbon monoxide toxicity/overdose
100% oxygen, hyperbaric oxygen
What is the antidote atropine used to treat?
anticholinesterase toxicity/overdose
What is the antidote for methanol toxicity/overdose
Ethanol, dialysis, fomepizole
What is the antidote for opiods toxicity/overdose
Naloxone/naltrexone
What is the antidote for ethylene glycol toxicity/overdose
Ethanol, dialusis, fomepizole
What is the antidote for benzodiazepines toxicity/overdose
Flumazenil
What is the antidote for (TCA) Tricyclic Antidepressants toxicity/overdose
NaHCO3
What is the antidote for Heparin toxicity/overdose
Protamine
What is the antidote Deferoxamine used to treat?
Iron toxicity/overdose
What is the antidote for warfarin toxicity/overdose
vitamin K, fresh frozen plasma
What is the antidote Naloxone/naltrexone used to treat?
opioid toxicity/overdose
What is the antidote for tPA/streptokinase toxicity/overdose
aminocaproic acid
What is the antidote Physostigmine salicylate used to treat?
Antimuscarinic/anticholinergic agents toxicity/overdose
What is the antidote Flumazenil used to treat?
Benzodiazepine toxicity/overdose
What is the antidote Protamine used to treat
Heparin toxicity/overdose
Children living in old houses might eat the paint chips which could cause ____
Lead Poisoning
Signs of Lead poisoning include:
Lead Lines on gingivae and epiphyses of Long bones, Encephalopathy and Erythrocyte nasophilic stippling, Abdominal colic and sideroblastic Anemia, wrist and foot Drop
LLLEEAAD
1st line of Treatment for Lead Poisoning include
Dimercaprol and eDta (leaDD) Succimer for kids (it sucks to be a kid who eats lead)
Weak acids, such as phenobarbitol, methotreaxate, aspirin, alkanize urine with ____ to increase clearance
bicarbonate
Weak bases, such as amphetamines, acidify urine with NH4Cl to ____ clearance
increase

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