Antimicrobial Drugs - Buzzwords
Terms
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- Calcium chelator
- Tetracycline
- Brown teeth
- Tetracycline
- Gray-baby syndrome
- Chloramphenicol
- Oto- and nephrotoxicity
- Vancomycin, aminoglycosides
- Optic neuritis
- Ethambutol
- Polyarthralgia
- Pyrazinamide
- Induces cytochrome P450
- Rifampin
- Red-man syndrome
- Vancomycin
- Pseudomembranous colitis
- Clindamycin
- Kernicterus
- Sulfonamides
- Megaloblastic anemia (supplement with vitamin B6)
- Trimethoprim-sulfamethoxazole
- Cartilage damage, tendonitis
- Fluoroquinolones
- Orange bodily fluids
- Rifampin
- Fast vs. slow acetylators
- Isoniazid
- Infusion-related toxicity
- Amphotericin B
- D-Ala-D-Ala
- Vancomycin
- PBP3
- Aztreonam
- Blocks peptidyltransferase
- Chloramphenicol
- Blocks peptide bond formation
- Clindamycin
- Blocks ribosomal translocation by preventing exit of tRNA
- Macrolides
- Inhibits initiation complex, causes mRNA misreading, blocks translocation
- Aminoglycosides
- Blocks tRNA binding to ribosome
- Tetracycline
- Bactericidal for H. flu, S. pneumo, N. meningitidis
- Chloramphenicol
- Blocks initiation step of protein synthesis
- Linezolid
- PABA analogue
- Sulfonamides
- Prevents synthesis of dihydrofolic acid
- Sulfonamides
- Inhibits dihydropteroate synthetase
- Sulfonamides
- Prevents synthesis of tetrahydrofolic acid
- Trimethoprim
- Inhibits dihydrofolate reductase
- Trimethoprim
- Resistance is due to rRNA methylation
- Clindamycin, macrolides
- DNA gyrase, topoisomerase IV
- Fluoroquinolones
- RNA polymerase
- Rifampin
- Inhibits mycolic acid synthesis
- Isoniazid
- Inhibits arabinogalactan synthesis
- Ethambutol
- Inhibits microtubule function
- Griseofulvin
- Inhibits beta(1,3)D-glucan synthetase
- Caspofungin
- Binds ergosterol
- Amphotericin B, nystatin
- Inhibits lanosterol demethylation by cytochrome P450
- Azoles
- Inhibits thymidylate synthase
- Flucytosine
- Used to treat cryptococcal meningitis
- Flucytosine
- Used for meningococcal prophylaxis
- Rifampin
- Used to treat Pseudomonas infection in CF patients
- Fluoroquinolones
- Used to treat nocardiosis
- Sulfonamides
- Used to treat VRE, MRSA, PRSP
- Linezolid
- Used to treat C. perfringens and B. fragilis
- Clindamycin
- Used to treat Mycoplasma pneumoniae
- Tetracycline
- Used to treat chlamydia
- Tetracycline
- Used to treat Legionella
- Macrolides
- Used to treat gonorrhea
- Ceftriaxone
- Used to treat H. flu meningitis
- Chloramphenicol