Drug Interactions
Terms
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- bleomycin, amiodarone, busulfan
- Pulmonary fibrosis (3)
- isoniazid, halothane
- Hepatitis (2)
- halothane, valproic acid (used intonic and absence seizures), acetaminophen, amanita phalloides
- Focal to massive hepatic necrosis (4)
- penicillin
- Anaphylaxis (1)
- hydralazine, INH, procainamide, phenytoin
- SLE-like syndrome (4). [mnemonic: it's not HIPP to have lupus]
- sulfonamides, INH, aspirin, ibuprofen, primaquine, nitrofurantoin, pyrimethamine, chloramphenicol
- Hemolysis in G6PD-deficient patients (8)
- OCPs (e.g. estrogens and progestins)
- Thrombotic complications (1 class)
- withdrawal of glucocorticoids causes hypothalamic-pituitary-axis suppression
- Adrenocortical insufficiency (withdrawal of what class of drugs causes adrenocortical insufficiency?)
- Sulfonamides, amiodarone, tetracycline
- Photosensitivity reactions (3) [mnemonic: SAT for a photo]
- barbiturates, phenytoin, carbamazepine, rifampin, griseofulvin, quinidine
- Induce P-450 system (6)
- cimetidine, ketoconazole, grapefruit, erythromycin, INH, sulfonamides
- Inhibit P-450 system (6, including one fruit)
- sulfonamides, furosemide, methicillin, rifampin, NSAIDs (except aspirin)
- Tubulointerstitial nephritis (5)
- Tamoxifen
- Hot flashes (1)
- niacin, Ca++ channel blockers, adenosine, vancomycin (red man syndrome)
- Cutaneous flushing (4)
- doxorubicin (adriamycin), daunorubicin
- Cardiac toxicity (2)
- clozapine (atypical antipsychotic), carbamazepine(monitor LFT weekly), colchicine
- Agranulocytosis (3, all start with letter C)
- ethosuximide, sulfonamides, lamotrigine
- Stevens-Johnson syndrome (3)
- quinidine, quinine
- Cinchonism (2)
- fluoroquinolones
- Tendonitis, tendon rupture and cartilage damage (kids) (1)
- metronidazole, certain cephalosporins, procarbazine, sulfonylureas
- Disulfiram-like reaction (4)
- aminoglycosides, loop diuretics, cisplatin
- Otoxicity and nephrotoxicity (3)
- haloperidol, chlorpromazine, resperine (blocks the formation of dopamine or NE from tyrosine), MPTP
- Drug-induced Parkinson's (4)
- Class III (sotalol), class IA (quinidine) antiarrhythmics
- Torsades de pointes (two subclasses of antiarrhythmics)
-
chloramphenicol, benzene, NSAIDs
Parvo virus B19 - Aplastic anemia (3) and a virus
- polymyxins
- Neuro/nephrotoxicity (1)
- clindamycin, ampicillin
- Pseudomembranous colitis (2)
- spironolactone, digitalis, cimetidine, chronic Alcohol use, estrogens, ketoconazole
- Gynecomastia (5) [mnemonic: Some Drugs Create Awesome Knockers]
- tricyclics
- Atropine-like side effects (1)
- ACE inhibitors (losartan --> no cough)
- Cough (1)
- phenytoin
- Gingival hyperplasia (1)
- lithium
- Diabetes insipidus (1)
- antipsychotics
- Tardive dyskinesia (1)
-
tetracycline
impaired proximal tubular reabsorption 2° to lead poisoning or Tetracycline (glycosuria, hyperphosphaturia, aminoaciduria, systemic acidosis) - Fanconi's syndrome (1)
- chloramphenicol
- Gray baby syndrome (1)
- chlorpromazine, thioridazine, haloperidol (these are all typical antipsychotics)
- Extrapyramidal side effects (3)
- corticosteroids, heparin
- Osteoporosis (2)
- Monday Disease ·
- Nitroglycerin Industrial exposure ® tolerance during week ® loss of tolerance during weekend ® headache, tach, dizziness upon re-exposure
- Rifampin
- Orange Body Fluids ·
- Vancomycin
- Red Man Syndrome ·
- MAOIs
- Severe HTN with Tyramine ·
- Aspirin and Quinidine
- Tinnitus ·