Pigmented lesions
Terms
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- What is another name for physiologic (racial) pigmentation?
- Melanoplakia
- Name the most common location for physiologic (racial) pigmentation/melanoplakia.
- Attached gingiva
- What causes physiologic (racial) pigmentation/melanoplakia?
- Increased ACTIVITY (not number) of melanocytes
- Name two risk factors (besides smoking) for Smoker's Melanosis.
- 1 Female 2 Females on the Pill
- Name the three most common areas to see Smoker's Melanosis.
- 1 Mandibular anterior (gingiva) 2 Buccal mucosa 3 Palate
- Is Smoker's Melanosis premalignant?
- No, not alone
- Does Smoker's Melanosis go away after quitting smoking?
- Yes, probably
- T/F: Oral Melanotic Macules are due to sun-exposure.
- False, freckles are
- What disease histologically features an increase in melanin granules, which is confined to the basal cell layer?
- Oral melanotic macule
- What is the most common of all human 'tumors'?
- Pigmented Cellular Nevus/ Acquired melanocytic nevus/Mole
- Name 2 synonyms for a mole.
- 1 Pigmented Cellular Nevus 2 Acquired melanocytic nevus
- What's the difference between a mole and a freckle (ephelis)?
- A mole does NOT depend on sun exposure; freckles do.
- What do nevus cells look like (4)?
- 1 Large 2 Oval 3 Epithelioid 4 Arranged in clumps
- What type of mole do all moles start out as?
- Junctional nevus
- What variant of mole is the second most common intraoral nevus?
- Blue
- Malignant melanoma is the (#) most common skin cancer. ____% of skin melanomas occur in the head/neck area. (Chronic/acute) sun damage is more important when it comes to malignant melanoma. The lifetime risk for a __(ethnicity)__ to get malignant melanom
- 3rd most common. 25% in head and neck. Acute is worse. Caucasians 1:100 will get them.
- What is the most common type of Malignant melanoma?
- Superficial spreading melanoma
- What type of Malignant melanoma is multicolored and flat?
- Superficial spreading melanoma
- 1/3 of this type of Malignant melanoma are in the head and neck area.
- Nodular melanoma
- What type of Malignant melanoma is elevated, and sometimes has no pigmentation?
- Nodular melanoma
- What type of Malignant melanoma is melanoma in situ?
- Lentigo maligna melanoma
- What is the most common type of oral Malignant melanoma?
- Acral lentiginous melanoma
- Name the two most common sites for oral Malignant melanoma.
- 1 Maxillary anterior mucosa 2 Hard palate
- Most oral Malignant melanomas are (primary/metastatic) and have (good/bad) prognosis.
- Metastatic, bad
- How does Addison's disease manifest in the skin/mucous membranes?
- Bronzing
- What are two clinical features of Peutz-Jeghers Syndrome?
- 1 Oral freckles (melanotic macules) 2 Intestinal polyposis