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USMLE Step2 Secrets Signs/Syndromes


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Beck's triad
Jugular venous distention, muffled heart sounds, and hypotension in cardiac tamponade
Brudzinski's sign
Pain on neck flexion with meningeal irritation (meningitis)
Charcot's triad
fevers or chills, jaundice, and RUQ pain with cholangitis
Chvostek's sign
Tapping on the facial nerve elicits tetany in hypocalcemia
Courvoisier's sign
a painless, palpable gallbaldder plus jaundice equals pancreatic cancer
Cullen's sign
bluish discoloration of periumbilical area from retropertioneal hemorrhage (pancreatitis)
Cushing's reflex
hypertension, bradycardia, and irregular respirations with high intracranial pressure
Grey Turner's sign
bluish discoloration of flank from retroperitoneal hemorrhage (think pancreatitis)
Homan's sign
calf pain on forced dorsiflexion of the foot with deep venous thrombosis
Kehr's sign
pain in the left shoulder with ruptured spleen
Leriche's syndrome
claudication and atrophy of the buttocks with impotence (aortoiliac occlusive disease)
McBurney's sign
tenderness at McBurney's point with appendicitis
Murphy's sign
arrest of inspiration when palpating under the rib cage on the right with cholecystitis
Ortolani's sign/test
palpable or audible clikc in congenital hip dysplasia caused by abducting infant's flexed hips
Prehn's sign
elevation of a painful testicle that relieves pain in epididymitis (vs testicular torsion)
Rovsing's sign
pain at McBurney's point in appendicitis that is caused by pushing on left lower quadrant
Tinel's sign
paresthesias in carpal tunnel syndrome elicited by tapping on the volar surface of the wrist
Trousseau's sign
carpopedal spasm (tetany) in hypocalcemia caused by pumping up a blood pressure cuff
Virchow's triad
stasis, endothelial damage, and hypercoagulability (deep venous thrombosis risk factors)

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