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*USMLE 1 First Aid Classic findings


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often precedes squamous cell carcinoma
actinic keratosis
primary adrenocortical deficiency
Addison's disease
polyostotic fibrous dysplasia
Albright's syndrome
albuminocytologic dissociation
(+ protein in CSF with only modest + in cell count)
hereditary nephritis with nerve deafness
Alport's syndrome
anti-basement membrane
Goodpasture's syndrome
anti-centromere antibodies
scleroderma (CREST)
anti-double-stranded DNA antibodies (ANA antibodies)
SLE (type III hypersensitivity)
anti-epithelial cell
pemphigus vulgaris
anti-gliadin antibodies
celiac disease
anti-histone antibodies
drug-induced SLE
anti IgG antibodies
rheumatoid arthritis
anti-mitochondrial antibodies
primary biliary cirrhosis
anti-neutrophil antibodies
antiplatelet antibodies
idiopathic thrombocytopenic purpura
Marfan's syndrome
Argyll Robertson pupil
cerebellar tonsilar herniation
Arnold-Chiari malformation
Aschoff bodies
rheumatic fever
atrophy of the mamillary bodies
Wernicke's encephalopathy
Auer rods
acute myelogenous leukemia (esp. the promyelocytic type)
sickle cell anemia
Babinski's sign
UMN lesion
Baker's cyst in popliteal fossa
rheumatoid arthritis
"bamboo spine" on x-ray
ankylosing spondylitis
Bartter's syndrome
basophilic stippling of RBCs
lead poisoning
defective dystrophin; less severe than Duchenne's
Becker's muscular dystrophy
LMN CN VII palsy
Bell's palsy
Bence Jones proteins
multiple myeloma (kappa or lambda Ig light chains in urine)
IgA nephropathy
Berger's disease
defect in platelet adhesion
Bernard-Soulier disease
bilateral hilar adenopathy, uveitis
Birbeck granules on EM
histiocytosis X (eosinophilic granuloma)
bloody tap on LP
subarachnoid hemorrhage
"blue bloater"
chronic bronchitis
breast with blue-domed cysts
fibrocystic change of breast
blue sclera
osteogenesis imperfecta
boot-shaped heart on x-ray
- Tetrology of Fallot
Bouchard's nodes
osteoarthritis (PIP swelling secondary to osteophytes)
branching rods in oral infection
Actinomyces israelii
"brown tumor" of bone (2)
bone hemorrhage from:

1. Hyperparathyroidism

2. Osteitis Fibrosa Cystica
(von Recklinghausen's disease)
Brushfield's spots
Down's syndrome
X-linked agammaglobulinemia
Bruton's disease
posthepatic venous thrombosis
Budd-Chiari syndrome
8:14 translocation; associated with EBV
Burkitt's lymphoma
Burton's lines
lead poisoning
cafe au lait spots on skin
Caisson disease
Nitrogen gas emboli
calf pseudohypertrophy
Duchenne's muscular dystrophy
Call-Exner bodies
granulosa-theca cell tumor of the ovary
cardiomegaly with apical atrophy
Chagas' disease
Bug causing:
cerebriform nuclei
mycosis fungoides
(cutaneous T-cell lymphoma)
Chagas' disease bug
trypanosome infection
primary syphilis (painless)
chancroid bug
haemophilus ducreyi (painful)
- nystagmus;
- intention tremor;
- scanning speech
- cholangitis:
jaundice; RUQ pain; fever
Multiple Sclerosis
(Charcot's triad)
Charcot-Leyden crystals in lung

(eosinophil membranes)
phagocyte deficiency
Chediak-Higashi disease
cherry-red spot on the macula
Tay Sachs
breathing problem caused by central apnea in CHF and increased intracranial pressure
Cheyne-Stokes respirations
"""chocolate cysts"""
endometriosis (frequently involves both ovaries)
what chronic atrophic gastritis can lead to
gastric carcinoma
Chvostek's sign - facial muscle spasm upon tapping
clear cell adenocarcinoma of the vagina
DES exposure in utero
clue cells
gardnerella vaginitis
Codman's triangle on x-ray
bugs with Cold agglutinins (2)
mycoplasma pneumoniae & mononucleosis
cold intolerance
- hypothyroidism
- Raynauds
condylomata lata
secondary syphilis
continuous machinery murmur
patent ductus arteriosus
debranching enzyme deficiency
Cori's disease
Cotton-wool spots
chronic hypertension
cough, conjunctivitis, coryza & fever
councilman bodies in liver
toxic or viral hepatitis
Cowdry type A bodies
crescents in Bowman's capsule
rapidly progressive crescentic glomerulonephritis
congenital unconjugated hyperbilirubinemia
Crigler-Najjar syndrome
acute gastric ulcer associated with severe burns
Curling's ulcer
bug causing currant-jelly sputum
Curschmann's spirals in lung
Bronchial Asthma

(whorled mucous plugs)
acute gastric ulcer associated with CNS injury
Cushing's ulcer
depigmentation of neurons in substantia nigra
Parkinson's disease
dermatitis, dementia, diarrhea
Pellagra (Vit B-3: Niacin deficiency)
exophthalmos + lesions of skull + diabetes insipidus
Hand-Schuller-Christian disease

H: Huge Eyes
S: Skull lesions
C: Continuous urination
bug from dog or cat bite
pasteurella multocida
Donovan bodies
granuloma inguinale
post-MI fibrinous pericarditis
Dressler's syndrome
congenital conjugated hyperbilirubinemia (black liver)
Dubin-Johnson syndrome
deleted dystrophin gene (X-linked recessive)
Duchenne's muscular dystrophy
eburnation - polished, ivory-like appearance to bone
genetic disorder w/ rockerbottom feet, low-set ears and heart disease
Edward's syndrome (Trisomy 18)
uncorrected L to R shunt that becomes a R to L shunt
Eisenmenger's complex
elastic skin
Ehlers-Danlos syndrome
"waiter's tip"
Erb-Duchenne palsy: superior trunk brachial plexus injury
erythema chronicum migrans
Lyme disease
proximal tubular reabsorption defect
Fanconi's syndrome
fatty liver
ferruginous bodies in lung
colon polyps with osteomas and soft tissue tumors
Gardner's syndrome
glucocerebrosidase deficiency
Gaucher's disease
Ghon focus
primary TB
benign congenital unconjugated hyperbilirubinemia
Gilbert's syndrome
defect in platelet aggregation
Glanzmann's thrombasthenia
autoantibodies against alveolar and glomerular basement membrane proteins
Goodpasture's syndrome
idiopathic polyneuritis causing ascending paralysis
Guillan-Barre syndrome
"hair-on-end" appearance (hairy skull) on x-ray
- beta-thalassemia
- sickle cell anemia
(extramedullary hematopoeisis)
another name for:

chronic progressive histiocytosis
Hand-Schuller-Christian disease
sickle cell anemia
hCG elevated

H: Hydatidiform moles

C: Choriocarcinoma of Gonads
Heberden's nodes
(DIP swelling secondary to osteophytes)
Heinz bodies
G6PD deficiency
hypersensitivity vasculitis associated with hemorrhagic urticaria on lower body, GI problems and URIs
Henoch-Schonlein purpura
heterophil antibodies
infectious mononucleosus (EBV)
thalassemia major
vitamin problem causing high-output cardiac failure
(dilated cardiomyopathy)
wet beriberi (thiamine deficiency)
HLA B27 (2)
- Reiter's syndrome,
- Ankylosing Spondylitis
HLA DR3 or -DR4
diabetes mellitus type 1 (caused by autoimmune destruction of beta cells)
Homer Wright rosettes
honeycomb lung on x-ray
interstitial fibrosis
ptosis, miosis & anhydrosis
Horner's syndrome (Pancoast tumor)
Howell-Jolly bodies in blood
splenectomy (or nonfunctional speen)
caudate degeneration (autosomal dominant)
Huntington's disease
hyperphagia + hypersexuality + hyperorality + hyperdocility
Kluver-Bucy syndrome (amygdala)
hyperpigmentation of the skin
primary adrenal insufficiency (Addison's disease)
hypersegmented neutrophils
macrocytic anemia
hypertension + hypokalemia
Conn's syndrome
hypochromic microcytosis
- iron deficiency anemia,
- lead poisoning
abnormally increased alpha-fetoprotein in amniotic fluid / maternal serum
neural tube defects
increase uric acid levels (4)
- Gout,
- Lesch-Nyhan syndrome,
- myeloproliferative disorders,
- loop & thiazide diuretics
Virus causing: intussusception

(causes hyperplasia of Peyer's patches)
Janeway lesions
neutrophil chemotaxis abnormality
Job's syndrome
Karposi's sarcoma
AIDS in MSM (men who have sex with men)
dynein defect
Kartagener's syndrome
Kayser-Fleischer rings
Wilson's disease
Keratin pearls
squamous cell carcinoma
pink Kimmelstein Wilson nodules of the nephron
diabetic nephropathy
bilateral amygdala lesions
Kluver Bucy syndrome
Koplik spots
gastric adenocarcinoma with ovarian metastases
Krukenberg tumor
Kussmaul hyperpnea
1. DKA

2. Constrictive Pericarditis
lens dislocation + aortic dissection + joint hyperflexibility
Marfan's syndrome (fibrillin defect)
HGPRT deficiency
Lesch Nyhan syndrome
Lewy bodies
Parkinson's disease
endocarditis associated with SLE
Libman Sacks disease
Lines of Zahn
arterial thrombus
Lisch nodules on arms
(von Recklinghausen's disease)
low serum ceruloplasmin
Wilson's disease
Lucid interval
epidural hematoma
"lumpy bumpy" appearance of glomeruli on immunofluorescence
poststreptococcal glomerulonephritis
lytic bone lesions on x-ray
multiple myeloma
Mallory bodies in the liver
alcoholic liver disease
esophagogastic lacerations
Mallory-Weiss syndrome
muscle phosphorylase deficiency
McArdle's disease
McBurney's sign
MLF syndrome (INO)
multiple sclerosis
monoclonal antibody spike
multiple myeloma (called the M protein; usually IgG or IgA)
necrotizing vasculitis (lungs) and necrotizing glomerulonephritis
- Wegener's
- Goodpasture's
(hemoptysis and glomerular disease)
needle-shaped negatively birefringed crystals
Negri bodies
nephritis + cataracts + hearing loss
Alport's syndrome
neurofibrillary tangles
Alzheimer's disease
sphingomyelinase deficiency
Niemann Pick disease
no lactation postpartum
Sheehan's syndrome (pituitary infarction)
nutmeg liver
cancer from occupational exposure to asbestos
malignant mesothelioma
"Orphan Annie" nuclei
papillary carcinoma of the thyroid
Osler's nodes
Bug: owl's eyes in cell
painless jaundice
pancreatic cancer (head)
palpable purpura on legs and buttocks
Henoch Schonlein purpura
bronchogenic apical tumor associated with Horner's syndrome
Pancoast's tumor
rheumatoid arthritis
nigrostriatal dopamine depletion
Parkinson's disease
periosteal elevation on x-ray
pyogenic Osteomyelitis
benign polyposis; discolored mouth lesions
Peutz-Jeghers syndrome
Peyronie's disease
penile fibrosis
Philadelphia chromosome (bcr-abl)
CML (may sometimes be associated with AML)
Pick bodies
Pick's disease
Progressive dementia similar to Alzheimer's
Pick's disease
"pink puffer" (name the 2 types)
- centroacinar [smoking]
- panacinar [alpha-1-antitrypsin deficiency]
esophageal webs with iron deficiency anemia
Plummer-Vinson syndrome
gout (MP joint of hallux)
podocyte fusion
minimal change disease
polyneuropathy, cardiac pathology & edema
wet beriberi (thiamine deficiency)
polyneuropathy preceded by GI or respiratory infection
Guillan-Barre syndrome
lysosomal glucosidase deficiency associated with cardiomegaly
Pompe's disease
port-wine stain
positive anterior "drawer sign"
anterior cruciate ligament injury
vertebral tuberculosis
Pott's disease
pseudopalisade tumor cell arrangement in brain
glioblastoma multiforme
pseudorosettes in bone tumor
Ewing's sarcoma
rash on palms and soles (2)
- secondary syphilis;
- Rocky Mountain Spotted fever
recurrent vasospasm in distal extremities
Raynaud's syndrome
RBC casts in urine
acute glomerulonephritis
recurrent pulmonary Pseudomonas and S. aureus infections
cystic fibrosis
red urine in the morning
paroxysmal nocturnal hemoglobinuria
Reed-Sternberg cells
Hodgkin's lymphoma
Reid index (increased)
chronic bronchitis
Reinke crystals
Leydig cell tumor
urethritis, conjunctivitis, arthritis
Reiter's syndrome
renal cell carcinoma + Hemangiomas + adenomas
von Hippel-Lindau disease

V: Vesico-connected cancer
(vesico = bladder)
H: Hemangiomas
L: Large glands (Adenomas)
renal epithelial casts in urine
acute toxic/viral nephrosis
rhomboid crystals, positively birefringent
rib notching
coarctation of the aorta
Roth's spots in retina
congenital conjugated hyperbilirubinemia
Rotor's syndrome
Rouleaux formations (RBCs)
multiple myeloma
Russell bodies

(inclusions in plasma cells)
multiple myeloma
S3 heart sound
- L to R shunt
- mitral regurgitation,
- Left Ventricle failure
S4 heart sound
aortic stenosis
Schiller-Duval bodies
yolk sac tumor
senile plaques
Alzheimer's disease
cutaneous T-cell lymphoma
Sezary syndrome
postpartum pituitary necrosis
Sheehan's syndrome
Shwartzman reaction
Neisseria meningitidis
signet-ring cells
gastric carcinoma
Simian crease
Down's syndrome
Sipple's syndrome
MEN type IIa
dry eyes, dry mouth, arthritis
Sjorgen's syndrome
skip lesions
slapped cheek appearance
erythema infectiosum (fifth disease)
Smith antigen
"smudge cell"
soap bubble on the bone x-ray
giant cell tumor of bone
spike and dome on EM
membranous glomerulonephritis
Spitz nevus
benign juvenile melanoma
splinter hemorrhages in fingernails
starry-sky pattern
Burkitt's lymphoma
"strawberry tongue"
Scarlet fever
streaky ovaries
Turner's syndrome
string sign on abdominal x-ray
Crohn's disease
subepithelial humps on EM
poststreptococcal glomerulonephritis
Bug causing: suboccipital lymphadenopathy
Bug: sulfur granules
Actinomyces israelii
swollen gums, bruising, poor wound healing, anemia, bleeding from hair follicle
systolic ejection murmur (crescendo-decrescendo)
aortic valve stenosis
Burkitt's lymphoma (c-myc activation)
Philadelphia chromosome
Follicular lymphomas (bcl-2) activation

[F: Fourteen]
tabes dorsalis
tertiary syphilis
tendon xanthomas (classically Achilles)
familial hypercholesterolemia
thumb sign on lateral x-ray
epitglottitis (Haemophilus influenzae)
thyroidization of kidney
CHRONIC pyelonephritis
chalky accumulations of uric acid in gout
"tram-track" appearance on LM"
membranoproliferative glomerulonephritis

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