pharm sympathomimetics
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- epinephrine, NE, isoproterenol, dopamine, and dobutamine are all________________
- catecholamines
- catecholamines are_____________________
- sympathomimetics
- name 5 catecholamines
- EPI, NE, Isoproterenol, dopamine, dobutamine
- what receptors does epinephrine act on?
- alpha-1, alpha-2, beta-1, beta-2 adrenergics
- what receptors does NE work on?
- alpha-1, alpha-2, beta-1 adrenergics
- what receptors does isoproterenol work on?
- beta-1 = beta-2 adrenergics
- what receptors does dopamine work on?
- D1 = D2, D1 and D2 more than beta, beta more than alpha
- what receptors does dobutamine work on?
- beta-1 > beta-2
- which catecholamines are agonists to alpha-adrenergic receptors
- EPI, NE > dopamine
- which catecholamines are agonists to beta-1 adrenergic receptors
- EPI, NE, Isoproterenol, dopamine, dobutamine
- which catecholamines are agonists to beta-2 adrenergic receptors
- EPI, isoproterenol, dopamine and dobutamine (less)
- what is epinephrine used to treat?
- anaphylaxis, open-angle glaucoma, asthma, hypotension
- what is norepinephrine used to treat?
- hypotension (but decreases renal perfusion)
- what is isoproterenol used to treat?
- AV block, asthma
- what is dopamine used to treat
- shock with renal failure, heart failure
- what is dobutamine used to treat
- shock, heart failure
- what catecholamine is used to treat anaphylaxis
- epinephrine ("EPI-pen")
- what catecholamines are used to treat hypotension
- EPI, NE
- what catecholamine is used to treat asthma
- epinephrine
- what catecholamine is used to treat AV block
- isoproterenol
- what catecholamines are used to treat shock
- doapmine, dobutamine
- what is the action of amphetamine
- indirect general adrenergic agonist, releases stored catecholamines
- what is the action of ephedrine
- indirect general adrenergic agonist, releases stored catecholamines
- what is amphetamine used to treat
- narcolepsy, obesity, attention deficit disorder
- what is ephedrine used to treat
- nasal decongestion, urinary incontinence, hypotension
- name three sympathomimetic drugs used to treat hypotension
- epinephrine, norepinephrin, ephedrine
- what is the action of phenylephrine
- adrenergic agonist, alpha-1 > alpha-2
- what is the action of albuterol
- adrenergic agonist, beta-2 >beta-1
- what is the action of terbutaline
- adrenergic agonist, beta-2 >beta-1
- what is phenylephrine used for?
- pupil dilator, vasoconstriction, nasal decongestion
- what sympathomimetics are used to treat nasal congestion
- ephedrine, phenylephrine
- what is the mechanism of cocaine
- indirect general adrenergic agonist, catecholamine uptake inhibitor
- what is the action of cocaine
- vasoconstriction, local anesthesia
- what is the mechanism of clonidine
- centrally acting alpha-adrenergic agonist, decreases central adrenergic outflow
- what drug has the same mechanism as amphetamine
- ephedrine
- what is the mechanism of alpha-methyldopa
- centrally acting alpha-adrenergic agonist, decreases central adrenergic outflow
- what drug has the same mechanism as clonidine
- alpha-methyldopa
- what are clonidine and alpha-methyldopa used to treat
- hypertension, especially in renal disease because they do not decreased blood flow to the kidney
- what sympathomimetic is used to treat urinary incontinence
- ephedrine
- what sympathomimetic is used to treat attention deficit disorder
- amphetamine
- what sympathomimetic is used to treat narcolepsy
- amphetamine