Anatomy 11/29/06
Terms
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copy deck
- What are the effects of smoking on goblet cells and why?
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-become sick, weaken and eventually die
-people inahle more nicotine than the mucus can trap
-nicotine can then get through - What is the effect of smoking on psudociliated colunar cells, what does this mean, what do they get replaced by?
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-become weak and eventually die
-don't have cells that move mucus
-psudostratefied squamous cells (like skin cells) - What happens when you lose mucus producing cells from smoking?
- -smoke can reach aveoli
- What happens when smoke reaches the aveoli?
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-particles get attacked by macrophages
-eventually get overrun and die - What's the effect of smoking on type 2 aveoli cells? What disease does this cause?
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-get damaged and don't produce surfactant and die
-emphazema
-can cause genetic change to cells that survive
-lung cancer - What is emphazima?
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-after aveolar cells get weakened enough for no gas exhange
-cells that line capillaries are killed next
-bleeding occurs and clog up (cough up blood)
-no blood supply, no fibroblasts - How do people who don't smoke get lung cancer?
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-2nd hand smoke
-genetic in family
-by chance (rare) - What is nicotine toxicity?
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-long term smokers get problems
-varicose veins
-adbominal problems
-etc.
-nicotine gets absorbed in bloodstream and affects entire body - What is the digestive system?
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-mechanical and chemical breakdown of what you ingested
-main rogans form GI tract (stomach, intestines) - What is the purpose of the digestive system?
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-acquiring fuel for your cells
-what you use gets absorbed
-what you don't use gets removed - What is Bolus?
- -food after being chewed up
- What do the superior and inferior labiral frenulum hold together? What problems could occur with them?
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-lips with oral cavity
-speech problems (need to be clipped) - What is the purpose of the liver?
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-produces bile for gallbladder
-refines molecules into a useable form - What does the gallbladder do?
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-emulsifies fat with bile
-"opens it up" - What are the tonsils a part of?
- -immune system
- What is amylase?
- -Saliva that breaks down large molecules (starches) and has anti-bacterial molecules
- What is the crown made of and where is it located on tooth?
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-made of enamel
-located on top of tooth - What is dentin and where is it located in the tooth?
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-harder than enamel
-located inferior to crown - What is the root canal and where is it located in the tooth?
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-contains nerves and blood vessels
-located within dentin - How are cavities formed?
- -bacteria eats away at crown
- What do the nerves in teeth do for us?
- -tells us when we need to get to the dentist due to bacteria getting into tooth
- What do the gingira do?
- -seals gums tight against teeth
- What is the root canal procedure?
- -when bacteria gets into tooth, dentist drills adn removes polarized nerve
- What are molecules that breakdown in the digestive system and what do they breakdown?
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-amylase (large molecules)
-protease (proteins)
-nucleolase (nucleic acids)
-liptase (lipids) - What is bile made from?
- -cholesterol
- What is a coloskopy?
- -investigate colon w/ cameras for polyps that can become cancerous
- What are the small intestines held to and by?
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-posterior body wall
-by mesenterys (nerves and blood supply of intestines) - What is the colon held up by?
- -by the mesocolon
- What is the stomach held by?
- -lesser omentum
- What does the greater omentum do?
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-hangs down over organs as a protective barrier
-holds adipose tissue
-when filled, extra fat fills peritoneal cavity (viseral fat) - What is the esophagus?
- -tube from pharnyx to stomach
- What epithelial layer is the esophagus made of?
- -stratefied squamous cells
- What is the superior 1/3 of the esophagus made of?
- -skeletal muscle
- What is the inferior 2/3 of the esophagus made of?
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-circular and longitudinal muscles
-smooth muscle - What are there voluntary and involuntary muscles of the esophagus?
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-so when you start swallowing, you finish
-you can't breath while you swallow - Where does the esophagus connect to the stomach? Why?
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-side of stomach
-top bulge (fundus)can hold pressure caused by moving - Why would people not be able to swallow? Who would have this?
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-neurological connection are malfunctioned
-elderly and mentally retarded - What is a Hiatal hernia?
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-diaphram teared by esophagus
-can be from totally insignificant with little discomfort to major issues
-can cut off blood supply to stomach and lead to death - What is peristalisis is digestion?
- -movement of bolus down the GI tract
- What is segementation in digestion?
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-mechanical breakdown of bolus and chyme
-by back and forth motions in the small intestines - What is chyme?
- -the product of broken down bolus by the swish-swoshing motion of the stomach
- What are oblique muscles of the stomach used for?
- -to prevent forward movement
- Why is there an oblique layer in the stomach?
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-to absorb food and drugs
-to store food until intestine needs it - Why are there gastric folds within the internal walls of the stomach?
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-so that the stomach can expand
-also called rugae - Where is the Mucosa layer of the GI tract located, what tissue is it made of, and what does it do?
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-external to lumen
-made of epithelial tissue
-made of loose connective tissue (lamina propria)
-the thin muscle layer causes circular folds (controlld by muscularis mucosae) - What is the purpose of circular folds?
- -to increase surface area and nutrient absorption
- Where is the Submucosa layer or the GI tract located, what does it contain, what does it do?
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-external to mucosa
-loaded with blood vessels
-major blood supply for absorption
-houses submucosal nerve plexus to turn on and off digestive system (post sypathetic/parasympathetic ganglionic neurons) - What does the muscularis layer of the GI tract contain?
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-contains both circular and longitudinal muscles (for movement of food)
-contains myenteric plexus which relax and contract muscles (sympathetic/ parasympathetic post ganglionic neurons) - Where is the serosa layer of the GI tract located, what is it made of, what membrane is it, and what does it produce?
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-most outermost layer
-loose connective tissue
-visceral membrane
-produces serous fluid - What is the purpose of segementation?
- -increases efficency of digestion and absorption
- What is the purpose of peristalsis?
- -to have food travel from esophagus to anus
- What happens when you eat too much?
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-expands and pushes pressue on liver, diaphram, and spleen
-may feel short of breath - What enzymes does the stomach produce?
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-mucin
-alkaline mucin
-intrinsic factor
-pepsinogen
-HCl- PH of 1
-gastin - What do surface mucous cells produce in the stomach?
- -secretes mucin
- What is the purpose of mucin?
- -to prevent ulceration and to protect the epithelium from gastric enzymes
- What do mucous neck cells secrete?
- -alkaline mucin
- What is the purpose of alkaline mucin?
- -to maintain acidic conditions
- What do parietal cells secrete?
- -hydrochloric acid and intrinsic factor
- What is HCl used for?
- -helps denature proteins for chemical digestion
- What is the purpose of intrinsic factor?
- -binds vitamin B12 and assists in its absorption in the ilieum of the small intestine
- What does the chief cell secrete?
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-secretes pepsinogen
-converted by acid into pepsin - What is the purpose of pepsin?
- -to chemically digest denatured proteins
- What do enteroendocrine cells secrete?
- -gastrin
- What is the purpose of gastin?
- -hormone that enters blood adn stimulates secretory activities of the chief and parietal cells and the contractile activity of the gastric muscle
- What are circular folds of the small intestines covered wtih?
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-intestinal villi which is covered with simple columnar microvillated epithelium
-to increase surface area
-goblet cells are spaced out