HTN/Repro Pharm
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- What are the side effects of ACE inhibitors and Angiotensin Receptor Blockers?
- Cough, angioedema, rash, hyperkalemia, CONTRAIND IN PREGNANCY
- What are the side effects of the beta blockers?
- bronchoconstriction (in asthmatics), sedation, hypoglycemia (diabetes)
- Which is the beta blocker with a niche in CHF because of its alpha 1 blocker (vasoldilator) activity?
- carvedilol
- Which antihypertensives can be used in Raynaud's syndrome and occasionally migraine?
- calcium channel blockers
- What are the side effects of calcium channel blockers?
- edema, headache, dizziness
- Which drug is a calcium channel blocker approved for the IV treatment of hypertension?
- nicardopine
- Which calcium blockers are more selective for vascular tissue?
- the dihydropyridines: amlodipine, nifedipine (short acting), felodipine
- What are some common calcium channel blockers that are not dihydorpyridines and their niches?
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diltiazem-depress AV conduction (mostly cardiac
verapamil-cardiac, also vasodil - Acts of the ENaC channel as a diuretic
- What is Triamterene
- Acts as an aldosterone antagonist and is rapidly gaining accceptance in the treatment of heart failure
- What is Eplerenone
- A CNS-acting antihypertensive that decreases sympathetic tone by stimulation of alpha 2 adrenergic receptors in CNS vasomotor areas. Causes vasodilation. (Side effs: dry mounth, sedation)
- What is clonidine
- Which drug has is a central acting potential NE antagonist with a niche in pregnancy-related eclampsia hypertensive emergencies?
- what is methyldopa
- What drug is an alpha 1 adrenerrgic antaganist that interrupts sympathetic vascular tone at the a1 receptor level in arterioles and veins?
- what is doxazosin
- What are the side effects of the alpha 1 adrenergic antagonists?
- edema, dizziness, headache and postural hypotension
- What are the adrenergic neuronal blockers that work by interfering with NE storage vesicles, causing depletion of NE? Side effs?
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Guanethidine, Reserpine.
diarrhea and parkinsonian effects, sedation. Contraind in depression.