nutrit review
Terms
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- vitamin K
-
coag 2,7,9,10 factor synthesis
absorb in jejunum in presence of bile salts, hence bile duct obst, colonic microflora = vit K deficiency - fat soluble
- A, E, D, K
- Water soluble
- B'S, (7), Folic acid, C, Zinc, Copper, Chromium, Iodine, Fe, Manganese
- B-1
-
Thiamine
Beriiberi, Wernicke's encephalopathy, - B-2
- Riboflavin, Cheilosis, seborrheic derm, angular stomatitis
- B-3
- Niacin, Pellagra, photo sens derm, diarrhea
- B-5
- Pantothenic Acid
- B-6
- Pyridoxine; CNS, seboor derm
- Biotin
- seborr derm
- B-12
- Cyanocobalamin; pernicious anemia, neural lesions
- Folic Acid
- Leukopenia, megaloblastic anemia, steatorrhea, sprue, glossitis
- Vit C
- retarded wound healing, scurvy, skin ulcers
- Zinc
- dermatitis, cerebelll dysfunction, abnl taste smell, depression
- copper
- anemia; water soluble
- obesity vs morbid obesity def
- 120% ideal weight vs. 150%
- coag pathway: intrinsic
- 12-11-9-8-5
- coag pathway extrinsic
- 7-10
- common coag pathway
- 10- 5- prothrombin to thrombin to act on fibrinogen to fibrin (loose) converted to (tight) by factor 8
- Pt evaluate which pathway and factors
- ability to form thrombin; extrinsic: 7, 10, 5. adequecy of prothrombin and fibrinogen
- APTT measures which pathway and factors?
- fibrinogen, prothombin, factors 5,8,9,10,11,12 in Intrinsic and commmon pathways. monitor heparin
- which PT or PTT normal in factor 7 def
- PTT
- coumadin therapy affects which PT or PTT and what factors involved
- PTT and factors 2, 9,10
- Prolonged Bleeding Time caused by
- thrombocytopenia, abnl platelet function (aspirin, granular platelet dis) or Von Willebrands dz
- Thrombin time is used to evaluate
- dic and chronic liver diz. also affect by heparin
- type A hemophilia
- dificiency of factor 8, males only, can be asymptomatic treated with factor 8 concentrates.
- hemophilia B, christmas disease
- defic. in factor 11.
- Von Willebrands treatment
- cryoprecipitate or DDAVP
- Liver dis coagulopathy
- inabil of liver to synthesize proteins and decreased prothrombin, factors 5,7,10 (but not 8)
- alcohol coagu
- acute thrombocytopenia
- coumadin
- depress 4 coag factors (2,7,9,10) prolonges both aptt, pt
- Heparin prolongs
- aptt and thrombin
- LMW heparin can
- bind antithrombin 3 and neutralize facotr Xa but not thrombin