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Psy 456 Neural Transmission

Physiological Psychology

Terms

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Ionotropic Receptors
Chemically gated ion chanels located on the post-synaptic membrane; fast.
Suprathreshold
Way above threshold level.
Threshold
A certian level of depolarization is needed before an action potential will occur.
Reuptake
The neurotransmitter in the synapse is pushed back into the pre-synaptic terminal so that it no longer binds to the receptors.
Nodes of Ranvier
Contain tightly packed ion channels, so reactivates the Action Potential when traveling down the axon.
Temporal Summation
A single synapse firing more than once back to back.
Post-synaptic
The neruon after the synapse.
Ion Channels
Channels that transport specific ions and must be activated to allow the ion flow.
Hyperpolarization
Move farther away from neutral midpoint.
Anions
Negative charged ions
Spatial Summation
The sum of multiple synapses firing at different locations at one time to create a net effect.
Transmembrane Proteins
Proteins in the plasma membrane that span across the entire membrane.
Synaptic Vesicles
Located in the terminal button and is small sacs of neurotransmitters.
Enkephalin/endorphin
Neuropeptide
Action Potential
aka Active Response, dynamic, not proportionally linked.
Nicotinic effects
Effects of neurotransmitters that increase CNS stimulation, respiration and muscle contraction.
Semi-Permeable Membrane
Plasma Membrane of the cell that controls what goes in and out of the cell.
Cations
Postive charged ions
Transduction
A change in form of energy.
Oscilloscope
Can use to visualize electric charge.
Neurotransmitter Substance
Neurotransmitters located in the synaptic vesicles.
Neural Transmission
Communication/effects on other neurons and cells of the body.
Propagation
How the Action Potential travels down the axon to terminals.
Neurotransmitter Receptor
The receptor on the post-synaptic membrane for the neurotransmitters.
Axon Hillock
Aka the initial segment; unmylenated and is where neural integration is assessed.
Reticular Theory of Nervous System
The idea that Nervous system is completely interconnected.
Depolarization
Move toward neutral midpoint.
Diffusion
Flow of high concentration to low concentration.
Neuron Theory
Theory that states the neuron is working unit.
Electrostatic gradient
Flow of high charge to low charge.
Mitochondria
Located in the terminal button and provides energy through ATP.
Sodium & Chloride
Found outside of cell.
Glutamate
An excititory Neurotransmitter.
Excitatory Post Synaptic Potentials (EPSP)
A minute depolarization that occurs after a neurotransmitter binds to the receptor and causes a decrease in the probability of an action potential.
Dopamine
Similar in structure to seretonin and norephinephrine, catechols.
Inhibitory Post Synaptic Potentials (IPSP)
A minute hyperpolarization that occurs after a neurotransmitter binds to the receptor and causes a decrease in the probability of an action potential.
Exocytosis
Pushed out of the cell.
Neural Muscular Junction
Conjuction between neural tissue and muscle tissue; Nicotinic ACH receptors found there.
Saltatory Propagation
Jumping from node of ranvier to next node of ranvier.
Mylenation
Larger diameter=faster, speed of neural transmission.
Resting Membrane Potential (RMP)
The voltage potential inside the cell at rest, -70mv.
Norephinephrine
Similiar in structure to dopamine and seretonin, Catechols.
Terminal Button
The structure of the neuron where the Action Potential ends.
Passive Response
Matched in terms of duration and amplitude.
Muscarinic effects
Effects of neurotransmitters that decrease heart rate and bladder capacity and increases glandular secretions.
Acetylcholine (ACH)
A neurotransmitter that is studied the most and can be either excititory or inhibitory.
Pre-synaptic
The neuron before the synapse.
Polarization
Move away from neutral midpoint.
Metabotropic Receptors
A receptor that uses second messengers to eventaually activate a separate ion chanel; slow, long lasting changes.
Seretonin
Similiar in structure to dopamine and Norephinephrine, catechols.
Reference
Measurement is relative to surrounding circumstances.
Microtubules
Located in the terminal button that provides structure and axonal transport.
Potassium
Found inside cell.
GABA
An inhibitory Neurotransmitter.
Circuits
Interconnected neurons that influence each other.
Enzymatic Degradation
The neurotransmitter in the synapse is broken down by an enzyme so that it no longer binds to the receptors.
Eflux
Go out of cell.
Influx
Driving molecules into cell because of concentration and electrostatic gradients.
Refractory Period
The period after hyperpolarization where another action potential cannot occur during this time.
Receptor Subtypes
Each neurotransmitter has a family of receptors that allows a different effect.
Microfilaments
Located in the terminal button that provides structure and axonal transport.

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