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Reproductive Physiology

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How often are GnRH pulses released in males?
every 90-120 minutes
What inhibits GnRH relase?
Testosterone
Estradiol
What do Leydig cells do?
Found between Seminiferous Tubules
Stimulated by LH
Release Testosterone
Inhibited by Estradiol/Testosterone
What do Sertoli cells do?
Stimulated by FSH
Spermatogenesis
Inhibited by Inhibin and Testosterone
What does T. do in fetal testis?
Differentiation of Wolffian ducts
Conversion to DHT
What does T. do age 3-6 months?
Priming of penile, prostatic, testicular growth
What does T. do at puberty?
Secondary sexual characteristics
Caps epiphyses
Name the stages of Spermatogenesis and the # of chromosomes at each step.
Spermatogonia (46)
Primary spermatocytes (92)
Secondary spermatocytes (46)
Round Spermatids (23)
Spermatozoa (23)
How long does it take to get from Spermatogonia to Spermatozoa?
64-74 days.
Where is sperms' motility acquired?
as it travels through epididymis
What are the two phases of the menstrual cycle called?
1-14: Follicular
15-28: Luteal
What effect does estradiol produced during the follicular phase have?
negative feedback to AP
What effect does estradiol produced during midcycle have?
Positive feedback to AP
What effect does progesterone produced during the luteal phase have?
Negative feedback to AP
When is the highest period of progesterone release during the menstrual cycle?
five days after ovulation (time of implantation)
When does HCG secretion begin?
eight days after ovulation (implantation has occured)
What converts Testosterone to Dihydrotestosterone
5alpha-reductase

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