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BRS Phys 1 Cell Physiology

Terms

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Proteins that span the entire cell membrane
Integral proteins
Membrane proteins that include Ion channels and Transport proteins
Integral proteins
Membrane proteins that are located on either the intracellular or extracellular side of the cell
Peripheral proteins
Membrane proteins that include Hormone receptors
Peripheral proteins
Zonula occludens alternate name
Tight junction
Attachments between cells that may be an intercellular pathway for solutes, depending on size, charge, and characteristics of the particular things I'm asking about

Tight jxn (Zonula occludens)
Are attachments between cells that permit intercellular communication
-Example: permit current flow and electrical coupling between Myocardial cells

Gap junctions
Describe the Na+, K+ ATPase pump
-transports 3 Na+ out of cell against its gradient

-transports 2 K+ into the cell against its gradient
What are 2 drugs that inhibit the Na+/K+ ATPase pump?
Oubain

Digitalis
Where is the H+/K+ ATPase at and what does it do?
Gastric Parietal Cells

transports H+ into the stomach lumen against its gradient
What drug inhibits the H+/K+ ATPase (proton pump) in Parietal Cells?
Omeprazole
Describe the Na+/glucose cotransport system in the intestinal mucosa and renal proximal tubule cells
-works by Secondary Active Transport
-Na+ is pumped out of the cell by the Na+/K+ ATPase
-this creates a downhill gradient for Na+ and glucose to come into the cell
-poisoning the Na+/K+ pump stops the Na+/glucose cotransport
The flow of water across a semipermeable membrane from a solution with low solute concentration to a solution with high solute concentration
Osmosis
When does Osmotic Pressure increase?
when the solute concentration increases
Which has a higher Osmotic pressure: 1 M CaCl2 or 1 M KCl?
1 M of CaCl2 b/c it has 3 particles compared to 2
Is the concentration of osmotically active particles in a solution
Osmolarity
What is the osmolarity of 1 M NaCl?
2 particles X 1 M = 2 osm/L
If the Reflection Coefficient is 1, the solute is _______.

What is an example?
Impermeable

Albumin
If the Reflection coefficient is 0, the solute is ______

What is an example?
completely permeable

Urea = does not exert any osmotic effect

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