Top 200 Drugs 1
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- What is the general MOA for narcotic analgesics?
- Bind to mu-opioid receptors, altering perception and response to pain.
- Diclofenac
- Voltaren, Cataflam, Flector
- Lodine
- Etodolac
- Relafen
- Nabumetone
- Nabumetone
- Relafen
- Naproxen
- Naprosyn, Anaprox, Aleve
- What is the MOA of NSAIDs?
- They inhibit COX-I and COX-II
- What is the MOA of Celebrex/Celecoxib?
- It is a selective COX-II inhibitor
- What is the dosage of Ibuprofen/Motrin/Advil?
- Adults: 200-800mg qid (OTC MDD is 1200mg), Children: 5-10mg/kg q 6-8 hours. Take with food.
- What is the dosage for Naproxen/Naprosyn/Anaprox/Aleve?
- Adult: 250-500mg q 8-12 hours, OTC 200mg 200mg q 8-12 hours. Take with food.
- Metformin
- Fortamet, Glucophage, Glucophage XR, Glumetza, Riomet (biguanide)
- Januvia
- Sitagliptin (DPP 4 Inhibitor)
- Sitagliptin
- Januvia (DPP 4 Inhibitor)
- Apidra
- Glulisine (rapid-acting insulin)
- Glulisine
- Apidra (rapid-acting insulin)
- Humalog
- Lispro (rapid-acting insulin)
- Lispro
- Humalog (rapid-acting insulin)
- Novolog
- Aspart (rapid-acting insulin)
- Aspart
- Novolog (rapid-acting insulin)
- What is the dosage for Metformin/Fortamet/Glucophage/Glucophage XR/Glumetza,Riomet?
-
IR: MDD is 2250mg
XR: MDD is 2000mg
usually qd or bid
take with food. - What are the onset, peak and duration of rapid acting insulin? (Apidra/Glulisine, Humalog/Lispro, and Novolog/Aspart)
- Onset 15 mins, peak 1 hour, duration 3 hours
- Humilin R, Novolin R
- Insulin regular (short-acting)
- What are the onset, peak and duration of regular insulin? (Humilin R, Novolin R)
- Onset 30 mins, peak 2-3 hours, duration 3-6 hours
- What are the onset, peak and duration of intermediate-acting insulin? (humilin N, novolin N, insulin NPH)
- Onset 2-4 hours, peak 6-10 hours, duration 10-16 hours
- Levemir
- Detemir (long acting insulin)
- Detemir
- Levemir (long acting insulin)
- What are the onset and duration of long-acting insulin? (levemir/detemir)
- Onset 4 hours, duration 12-24 hours
- Amaryl
- Glimepiride (sulfonylurea)
- Glimepiride
- Amaryl (sulfonylurea)
- Glucotrol, Glucootrol XL
- Glipzide (sulfonylurea)
- Glipzide
- Glucotrol, Glucotrol XL (sulfonylurea)
- What is the dosage of Glipzide/Glucotrol/Glucotrol XL?
-
IR: IDD is 2.5-5mg, MDD is 10-40mg qd
XL: IDD is 5mg, MDD is 5-20mg qd - DiaBeta, Micronase, Glynase Prestab
- Glyburide (sulfonylurea)
- Glyburide
- DiaBeta, Micronase, Glynase Prestab (sulfonylurea)
- What is the MOA of sulfonylureas?
- Lowers blood glucose by stimulating release of insulin from beta cells in pancreas.
- Actos
- Pioglitazone (thiazolidinedione)
- Pioglitazone
- Actos (thiazolidinedione)
- Laniazid, Nydrazid
- Isoniazid (antimycobacterial)
- Isoniazid
- Laniazid, Nydrazid (antimycobacterial)
- Rifadin, Rimactane
- Rifampin (antimycobacterial)
- Rifampin
- Rifadin, Rimactane (antimycobacterial)
- What is the dosage for Isoniazid/Laniazid/Nydrazid?
- 5mg/kg qd (MDD 300mg) OR 15mg/kg biw-tiw (MDD 900mg)
- Amoxil, Trimox
- Amoxicillin (penicillins)
- Amoxicillin
- Amoxil, Trimox (penicillins)
- What is the dosage for Amoxicillin/Amoxil/Trimox?
-
Adults: 250-500mg tid or 875 bid.
Children: 20-40mg/kg tid or 25-45mg/kg bid. - What is a side effect of Rifampin/Rifaden/Rimactane that you should counsel patients about?
- Rifampin will turn body fluids red/orange and can dye clothes or contact lenses.
- What are common drug interactions with acetaminophen?
-
Warfarin can have increased anticoagulant effects.
Taking w/ Isoniazid or ethanol may cause hepatotoxicity. - What are common drug interactions with Narcotic Analgesics?
-
CNS depressants have additive effect.
MAOi and SSRIs can cause serotonin syndrome. - Augmentin
- Amoxicillin/Clavulanate (penicillins)
- Amoxicillin and Clavulanate
- Augmentin (penicillins)
- Pen-VK, Beepen-VK, Veetids
- Penicillin
- Penicillin
- Pen-VK, Beepen-VK, Veetids
- What should you counsel patients about for Dolophine/Methadone?
-
Grapefruit juice will decrease its absorption.
Taper. - What are common drug interactions with NSAIDs?
- Corticosteroids and ethanol will increase GI upset/irritation. ACE Inhibitors will have decreased anti-hypertensive effect. Anticoagulants have increased risk for bleeding. Diuretics will have diminished effect.
- What NSAID can be used to treat for gout?
- Ibuprofen
- What NSAID can be used to treat myocardial infarction?
- Aspirin
- What drugs interact with aspirin?
- Ginkgo Biloba, varicella vaccine, other NSAIDs
- Cefzil
- Cefprozil (2nd gen. cephalosporin)
- Cefprozil
- Cefzil (2nd gen. cephalosporin)
- Ceftin
- Cefuroxime (2nd gen. cephalosporin)
- Cefuroxime
- Ceftin (2nd gen. cephalosporin)
- Rocephin
- Ceftriaxone (3rd gen. cephalosporin)
- Ceftriaxone
- Rocephin (3rd gen. cephalosporin)
- Keflex, Keftab
- Cephalexin (1st gen. cephalosporin)
- Cephalexin
- Keflex, Keftab (1st gen. cephalosporin)
- What is a 1st generation cephalosporin?
- Keflex/Keftab/Cephalexin
- What are the 2nd generation cephalosporins?
- Ceftin/Cefuroxime, Cefzil/Cefprozil
- What are the 3rd generation cephalosporins?
- Rocephin/Ceftriaxone
- What is the dosage for Penicillin/Pen-VK/Beepen-VK/Veetids?
- Adults: 250-500mg bid or tid
- Cipro
- Ciprofloxacin (Fluoroquinolones)
- Levaquin
- Levoflaxacin (fluoroquinolones)
- Ciprofloxacin
- Cipro (fluoroquinolones)
- Levoflaxacin
- Levaquin (fluoroquinolones)
- What is the dosage of Cipro/Ciprofloxacin?
- 250-750mg bid
- What is the dosage for Levaquin/Levoflaxacin?
- 250-750mg sid
- Avelox
- Moxifloxacin fluoroquinolones)
- Moxifloxacin
- Avelox (fluoroquinolones)
- Vancocin
- Vancomycin (glycopeptide)
- Vancomycin
- Vancocin (glycopeptide)
- Cleocin
- Clindamycin (lincosamide)
- Clindamycin
- Cleocin (linkosamide)
- Zithromax
- Azithromycin (macrolides)
- Azithromycin
- Zithromax (macrolides)
- Biaxin
- Clarythromycin (macrolide)
- Clarithromycin
- Biaxin (macrolide)
- E-Mycin
- Erythromycin (macrolide)
- Erythromycin
- E-Mycin (macrolide)
- Flagyl
- Metronidazole (Nitroimidazole)
- Metroidazole
- Flagyl (nitroimidazole)
- Bactrim, Septra
- Trimethoprim with sulfamethoxazole (folic acid antagonist)
- Trimethoprim with Sulfamethoxazole
- Bactrim, Septra (folic acid antagonist)
- Vibramycin
- Doxycycline
- Doxycycline
- Vibramycin
- Minocin
- Minocycline
- Minocycline
- Minocin
- What is the dosage for vibramycin/doxycycline?
-
Adults: 100mg bid
Do not use in children under 8! - What is the dosage of Minocin/Minocycline?
-
Adults: 200mg once, then 100mg bid.
Do not use in children under 8! - What is the MOA of tetracyclines? (Vibramycin/Doxycycline, Minocin/Minocycline)
- Bind to 30S chromosome, causing a bacteriostatic effect
- What are common drug interactions with tetracyclines? (vibramycin/doxycycline, minocin/minocycline)
- Cations will decrease absorptions. Warfarin will have enhanced effect. Oral contraceptives have decreased effect. Antibiotics will have decreased effect.
- What are common side effects of tetracyclines?
- It can cause permanent red/purple teeth discoloration in children
- Macrodantin
- Nitrofurantoin
- Nitrofurantoin
- Macrodantin
- What are common drug interactions for metformin?
- Do not use with contrast media.
- What is isoniazid used for?
- Tuberculosis
- What type of infection should amoxicillin be used for?
- H. pylori
- What type of infection should Penicillin be used for?
-
Streptococcal infections.
Anthrax.
Pneumococcal infections. - Amphocin
- Amphotericin B
- Amphotericin B
- Amphocin
- Diflucan
- Fluconazole
- Fluconazole
- Diflucan
- Sporanox
- Itroconazole
- Itroconazole
- Sporanox
- Vfend
- Voriconazole
- Voriconazole
- Vfend
- Zovirax
- Acyclovir
- Acyclovir
- Zovirax
- Valtrex
- Valacyclovir
- Valacyclovir
- Valtrex
- What is the dosage for Valtrex/Valacyclovir?
- 500-1000mg q 8-12 hours
- Zestoretic, Prinzide
- Lisinopril with hydrochlorothiazide
- Lisinopril with Hydrochlorothiazide
- Zestoretic, Prinzide
- Hyzaar
- Losartan with hydrochlorothiazide
- Lotrel
- Amlodipine with benazepril
- Losartan with Hydrochlorothiazide
- Hyzaar
- Amlodipine with benazepril
- Lotrel
- What is Valtrex/Valacyclovir used for?
- Genital herpes
- What should you counsel patients about when taking Amphocin/Amphotericin B?
- Side effects may include fever, chills or nausea. It can be minimized with acetaminophen or diphenhydramine.
- Ziac
- Bisoprolol with hydrochlorothiazide
- Bisoprolol wth hydrochlorothiazide
- Ziac
- Dyazide
- Triamterene with hydrochlorothiazide
- Triamterene with hydrochlorothiazide
- Dyazide, Maxzide
- Microzide
- Hydrochlorothiazide
- Hydrochlorothiazide
- Microzide
- What is the dosage for Microzide/Hydrochlorothiazide?
- 12.5-50mg qd
- Apresoline
- Hydralazine
- Hydralyzine
- Apresoline (vasodilator)
- Imitrex
- Sumatriptan
- Sumatriptan
- Imitrex
- What is the dosage for Imitrex/Sumatriptan?
-
PO: 25, 50, 100mg with MDD of 200mg.
Inject: 6mg with MDD of 12mg - Adipex-p, Ionamin, Fastin
- Phentermine
- Xanax, Niravam
- Alprazolam
- Phentermine
- Adipex-p, Ionamin, Fastin
- Alprazolam
- Xanax, Niravam
- What are Imitrex/Sumatriptan used for?
- Treats migranes
- What are Adipex-p/Ionamin/Fastin/Phentermine used for?
- Treats short term obesity
- Klonopin
- Clonazepam
- Clonazepam
- Klonopin
- Valium
- Diazepam (benzodiazepine)
- Diazepam
- Valium (benzodiazepine)
- Ativan
- Lorazepam (benzodiazepine)
- Lorazepam
- Ativan (benzodiazepine)
- Buspar
- Buspirone (non-benzodiazepine)
- Buspirone
- Buspar (non-benzodiazepine)
- What is the dosage for Buspar/Buspirone?
- 15-60mg/day in divided doses