Adrenergic Agonists
Terms
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What is the mechanism of nasal decongests?
Give examples -
Vasoconstriction of mucous membranes
Phenylephrine, Pseudoephedrine, Oxymetazoline (long acting) -
Name the 2 medications that are used to treat shock?
Which one inc. renal blood flow? -
Dopamine & Dobutamine
Dopamine - This medication prevents LA toxicity when used w/ local anesthetics
- Epinephrine
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These two medications are used for asthma?
What is the disadvantage of their use? -
Albuterol, terbutaline
Tolerance - This alpha agonist induces mydriasis
- phenylephrine
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This alpha-2 agonist acts on the ciliary body to dec. aqueous humor secretion?
What disease does its action benefit? -
Apraclonidine
Glaucoma - This prodrug of epinephrine penetrates the anterior chamber of the eye
- Dipevelfrin
- This amphetamine has a calming effect in hyperkinetic children
- methylphenidate (Ritalin)
- This is the DOC for treating allergic disorders (anaphyllaxis)
- Epinephrine (?)
- These are 2ndary treatments for anaphyllaxis
- glucorticoids, and antihistamines
- This medications can stimulate weight reduction
- amphetamine, phenylpropanolamine, phentermine
- This weight reduction drug stimulates the satiety center, induces tolerance and has less CNS stimulation than amphetamine
- phentermine
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This weight reduction drug increase 5HT release and reuptake,
What is its terrible side effect? - Fenfluramine - valvular heart disease, and pulmonary hypertension
- A new patient arrives with miosis, ptosis, dec. sweating, and a tumor in her sympathetic chain, what syndrome does she have?
- Horner's syndrome
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What does it mean if you give her an amphetamine and her pupils do not dilate?
How about the opposte (her pupils dilate)? -
Postganglionic nerve damage
Preganglionic nerve damage - Billy Hartatac arrives at your office for his annual visit, upon taking his standing blood pressure, you find that he has orthostatic hypotension. What 2 medications can you prescribe?
- Ephedrine, and Midodrine