Pharmacology 2
Terms
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- antagonist
- drug that binds to its recptor and prevents other drugs or substances from producing an effect
- generic name
- nonproprietary, or common, name of a drug
- Agonist
- drug that binds to its receptor and produces a drug action
- Drug dependence
- condition of reliance on the use of a particular drug characterized as physical and/or psychological dependence
- Adverse Effect
- general term for undesirable and potentially harmful drug effect
- Schedule 3 drug
- Drug with moderate abuse potential and accepted medical uses
- Drug microsomal metabolizing system (DMMS)
- group of enzymes located primarily in th eliver that function to metabolize (biotransform) drugs
- Loading dose
- initial drug dose administered to rapidly achieve therapeutic levels
- Bioavailability
- percentage of the drug dosage that is absorbed
- mechanism of action
- explanation of how a drug produces its effect
- Intravenous injection IV
- drug is injected into the vein
- Drug
- chemical substance that produces a change in body fuction
- Drug distribution
- pasage of a drug from the blood to the tissues and organs of the body
- Trade name
- patened proprietary name of a drug sold by a specific drug manufacturer
- ED50
- effective dose 50, or dose that will produce an effect that is half of the maximal response
- Drug absorption
- entrance of a drug into the bloodstream from its site of administration
- Parenteral administration
- route of drug administration that does not involve the gastointestinal tract GI
- Receptor
- specific location on a cell membrane or within the cell where the drug attaches toproduce its effect
- Mantinence dose
- dose administered to maintain drug levels in the therapeutic range
- Schedule V Drug
- drug with limited abuse potential and accepted medical use
- Drug Indications
- intended or indicated uses for any drug
- chemical name
- name that defines the chemical composition of a drug
- Enzyme induction
- increase in the amount of drug-metaboizing enzymes after repeated administration of certain drugs
- Side effect
- drug effect other than the therapeutic effect that is usually undesirable but not harmful
- LD50
- lethal dose 50, or a dose that will kill 50% of the animals tested
- Half-life
- time required for the body to rid itself of half of the drug dosage that was absorbed (percent bioavailability)
- Site of action
- location within the body where a drug exerts its therapeutic effect, often a type of receptor
- Dose
- exact amount of a drug that is administered in order to produce a specific effect
- Therapeutic effect
- desired drug effect to alleviate some condition or symptom of disease
- Contraindications
- situations or conditions when a certain drug should not be administered
- Schedule 1 Drug
- drug with a high abuse potential with no accepted medical use
- Schedule IV Drug
- drug with limited abuse potential and accepted medical uses
- Drug addiction
- condition of a drug abuse and drug dependence that is characterized by compulsive drug behavior
- Individual variation
- difference in the effects of drugs and drug dosages from one person to another due to genetics
- Toxic effect
- undesirable drug effect that implies drug poisoning, can be harmful or life threatening
- Therapeutic index (TI)
- ratio of the LD50 to the ED50
- Potency
- measure of the strength, or concentration, of a drug required to produce a specific effect
- Controlled substance
- drug that has the potential for abuse and thus is regulated by law
- Schedule 2 Drug
- drug with high abuse potential and some accepted medical uses
- Intramuscular injection IM
- route of drug administration, drug is injected into the gluteal or deltoid muscles