567 Pharm Exam 1 (set two)
Terms
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Brompheniramine
Chlorpheniramine
Dexchlorpheniramine
Triprolidine HCl -
Alkylamines
Brompheniramine (Bromphen, Dimetapp)
Chlorpheniramine (Chlortrimeton)
Dexchlorpheniramine (Dexchlor, Polarmine)
Triprolidine HCl (Actidil, Myidil) -
Carbinoxamine maleate/pseudoephedrine
Clemastine fumerate
Dimenhydrinate
Diphenhydramine -
Ethanolamines
Carbinoxamine maleate/pseudoephedrine
Clemastine fumerate (Tavist, Contact)
Dimenhydrinate (Dramamine)
Diphenhydramine (Benadryl, Allerdyl) - Triplennamine HCl
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Ethylenediamines
Tripplennamine HCl (PBZ, Pelamine, Triplennamine) - Promethazine
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Phenothiazines
Promethazine (Penazine, Phenergan, Phenerzine) -
Cyclizine
Meclizine -
Piperazines
Cyclizine (Marezine, Marzine)
Meclizine (Antivert, Bonine) -
Azatadine
Cyproheptadine
Phenidamine -
Piperidines
Azatadine (Optimine)
Cyproheptadine (Periactin)
Phenidamine (Nolahist) -
Hydroxyzine
Buclizine -
Misc.
Hydroxyzine (Vistaril, Atarax)
Buclizine (Bucladin-S)
-used for motion sickness, antiemetic, has anticholinergic properties -
Azelastine
Cetirizine
Fexofenadine
Levocabastine
Loratidine
Desloratidine -
2nd Gen. H1 Blockers
Azelastine (Astelin)
Cetirizine (Zyrtec, Reactine)
Fexofenadine (Allegra) - pediatric
Levocabastine (Livostin) - topical opthalmic for allergic conjunctivitis
Loratidine (Claritin) ped. OTC
Desloratidine (Clarinex) -Rx only - Why should you be familiar with what drugs you suggest your pt. take?
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-Some drugs with the same name have different ingredients, need to read package to know. -Some drugs have multiple ingredients with its corresponding action, interactions, etc.
-A patient may not need every ingredient in the drug.
-Dose must be sufficient to produce relief. - WHAT IS PHYSIOLOGICAL ROLE OF HISTAMINE?
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1.CNS neurotransmitter
2.Constriction of Smooth Muscle of Bronchial
3.Vasodilation
4.Increase capillary permeability
5.Gastrointestinal acid secretion
*USUALLY HISTAMINE plays a role to MEDIATE Inflammatory reactions associated with type I Hypersensitivity (allergies and anaphylactic shock)