N224 Pathophysiology - Pain - MSU - Huether, chapter 13
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- According to Chapter 13 what 3 systems interact to produce pain.
-
sensory/discrminative
motivational/affective
cognitive/evaluative - Name the two pathways and one system that are responsible for the sensation and perception of pain
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Afferent pathway
CNS
Efferent pathway - What is the term for a "Pain Receptor".
- Nociceptor - what is the definition
- Name two Nociceptors (that are corpuscles)
-
Meissner corpuscle
Pacinian corpuscle - Which pain receptor is located just under the epidermis.
- Meissner corpuscle
- Which pain receptor is located in deep tissues, muscles, tendons, and subcutaneous tissue.
- Pacinian corpuscle
- Which pathway are the nociceptors associated with?
- The Afferent pathway
- In the "Gate control theory" name the two fibers and their associated size.
-
Large A fibers
small C fibers - What does endorphin stand for?
- Endogenous Morphines
- What do endorphins do?
- they inhibit the transmission of pain impulses in teh spinal cord and brain.
- Where do endorphins attach or interact to cause the inhibition of pain impulses?
- Endorphins attach to Opiate Receptors on the plasma membrane of the afferent neuron.
- When endorphins attach to Opiate Receptors on the plasma membrane of the afferent neuron, what happens?
- this inhibits the release of neurotransmitters.
- Acute pain can be classified in what 3 categories?
-
Somatic
Visceral
Referred - Chronic pain is usually defined as lasting at least...?
- 3 to 6 months
- Define pain threshold.
- The lowest intensity at which a stimulus is perceived as pain.
- Define pain tolerance.
- The amount of time or intensity of pain that an individual will endure before initiating overt pain responses.