1.2 The Synapse and Neuron Transmitters
Terms
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- What are synaptic vesicles, and where are they located?
- Synaptic Vesicles are located in the terminal boutons of the presynaptic neuron and contain neurotransmitters...
- What are receptor sites?
- Pockets on the surface of the postsynaptic neuron which receive Neurotransmitter molecules.
- The activation of the receptor site has one of two oppsoite effects on the ion channel and on the dentritic potential of the post synaptic cell... what are they?
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EPSP
IPSP - What is EPSP?
- Excitatory Post-Synaptic Potential.. more likely to generate its own Action Potential
- What is IPSP?
- Inhibitory Post-Synaptic Potential...less likely to generate its own action potential
- How can you create action potential in the postsynaptic neuron?
- Through Spatial and Temporal Summation of EPSPs
- Definie Spatial Summation.
- Combining the effects of many EPSPs occuring SIMULTANEOUSLY from synapses all over receptive zone of postsynaptic neuron.
- Define Temporal Summation
- Combining the effects of a number of EPSPs that occur within a short time at the same synapse.
- Tricyclic antidepressants
- Blocks reuptake of norepinephrine and serotonin inro PREsynaptic neuron, keeps them in the synapses longer
- Prozac
- selective serotonin reuptake inhibitor (SSRI)... presynaptic cell
- Monoamine Oxidase (MAO)
- MAO breaks down monoamine neurotransmitters for reuse. MAO inhibitors used to treat depression, allows monoamine neurotransmitters to remain in cleft.