Alterations of Conscoiusness
Terms
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- What part of the brain does arousal depend on? Where is this located?
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1. RAS
2. Mid-pons to the hypothalamus - What parts of the brain does content depend on?
- The person must have some level of arousal accompanied by fuctional cortex, cortical-cortical and cortical-thalamic interconnections.
- What are three basic pathologic divisions of comas?
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1. Supratentorial (secondary impinged on RAS)
2. Infratentorial (directly damaged RAS)
3. Metabolic disorders (diffusely interferes w/ brain fxn) - What condition is described as having a rapid onset and fluctuations in level of awareness?
- Delirium
- What condition is described as reduction in alertness/lethargic?
- Obtundation
- What condition is described as a setting where the patient has to be constantly stimulated to maintain them/behavioral unresponsiveness?
- Stupor
- What condition is described as unarousable unresponsiveness?
- Coma
- What type of breathing is described as a repetitive cresendo-decresendo pattern? Where is the damage to the brain?
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1. Cheyne-Stokes
2. Bilateral hemispheric - What type of breathing is describes as big, fast, deep breaths that are continuous? Where is the damage to the brain?
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1. Tachypnea
2. Midbrain or upper pons - What type of breathing has end-inspiratory pauses followed by end-expiratory pauses? Where is the damage to the brain?
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1. Apneusis
2. Mid-pons - What type of breathing is described as irregular clusters of breathing separated by irregular time periods? Where is the damage to the brain?
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1. Cluster breathing
2. Lower pons to upper medulla - What type of breathing is described as having a chaotic rate and amplitude that is indicative of impending apnea?
- Ataxic breathing
- What is the best way to distinguish between a diffuse metabolic problem or a focal structural damage?
- Examine the pupils
- Metabolic problems show what type of pupils?
- Small reactive pupils
- Diencephalon/thalamic damage show what type of pupils?
- Small reactive pupils
- Tectal damage show what type of pupils?
- Large, fixed pupils with hippus
- CNIII damage shows what type of pupils?
- Fixed and dilated
- Pons damage shows what type of pupils?
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Pinpoint
"Pons = Pinpoint" - Midbrain damage show what type of damage?
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Midposition and fixed pupils
"Midbrain = Midposition" - Eyes should move conjugately in the direction opposite to head rotation
- Oculocephalic reflex (Doll's eyes)
- Cold calorics is which reflex?
- Oculovestibular reflex
- A full range of horizontal and vertical eye movements rules out what type of damage?
- Brainstem damage
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squirt cold water in both ears = ?
sprirt hot water in both ears = ? -
Look down
Look up
"Hot water good...so look UP and take your shower zilla!" - What two CNs does the corneal reflex test?
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CN V - feeling
CN VII - blinking - Gag reflex involves which CN(s)?
- CN's IX & X
- Decorticate posturing is flexion/extension?
- Flexion
- Decerebrate posturing is flexion/extension?
- Extension
- What is an uncal herniation a result of? What CN does this affect? What then happens?
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1. Unilateral supratentorial mass
2. CNIII - first unilateral pupillary diation, ptosis then full palsy.
3. It then can cause compression of the contralateral cerebral peduncle (KERNOHAN'S NOTCH) and bilateral hemplegia (false localizing sign) - What happens with progressive bilateral motor dysfunction
- Central transtentorial herniation
- What is a deterioration in cognitive abilities without a decline in arousal?
- Dementia
- What condition can be described as total loss of movement except for vertical eye movements and blinking. What part of the brain is damaged? What usually causes this?
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1. Locked in syndrome
2. Selective destruction of the base of the pons
3. Basilar artery thrombosis - What is STRICTLY defined as IRREVERSIBLE cessation of ALL functions of the brain INCLUDING brainstem
- Brain death
- How long must one be in a vegetative state to be considered in PVS?
- at least 1 month
- Pathology of PSV (persistent veg state)?
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widespread cortical destruction with INTACT brainstem (eyes roll, sleep-wake cycles but no meaningful movements)
sometimes called "cortical brain death"