Anes/Surgery 2
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- What are the effects of neuromuscular blockers?
- Paralyze only skeletal muscle (not visceral smooth muscle)-can't move or breath, but heart and GI muscle can function; no effect on CNS-no analgesia or sedation.
- What are some precautions to take when using a neuromuscular blocker?
- Admin after induction of general anes, intubate & ventilate patient, monitor for hypothermia & lubricat eyes.
- What are some uses for neuromuscular blockers?
- Thoracic, orthopedic or opthalmic surgery. Reintubation in laryngospasm. Not used much in vet med, mostly human.
- What is a type of neuromuscular blocker?
- Succinycholine.
- What is succinycholine used for?
- A neuromuscular blocker.
- What does succinycholine do to the muscle?
- It's a nondepolarizing muscle paralyzer
- What are some characteristics of succinycholine?
- Muscle twitch, followed by paralysis, fast onset, short duration, no reversing agent-must wear off.
- How does succinycholin work?
- It replaces acetylcholine at receptor & prevents receptor activation.
- How do depolarizing muscle paralyzers work?
- They compete with acetylcholine at receptor site.
- Dooes succinycholine have a reversing agent?
- No
- Do depolarizeing muscle paralyzers have a reversing agent?
- Yes, neostigmine.
- Do neuromuscular blockers paralzye skeletal or visceral smooth muscle?
- Skeletal.
- Do neuromuscular blockers have an affect on the CNS?
- No, there's no analgesia or sedation.
- What do you need to use with neostigmine?
- Pre-treat with Atropine.
- What are 5 types of neuromuscular blockers?
- Succinylcholine, depolarizing muscle paralyzers, gallamine, pancuronium bromide & curare.