Thyroid
Terms
undefined, object
copy deck
- Hypothyroidism Presentation
- cold intolerance, fatigue, somnolence, constipation, menorrhagia, myalgias, dry skin, weight gain
- Hypothyroid treatment
- Levothyroxine is drug of choice - Changes are made at 6-8 week intervals
- Levothyroxine counseling
-
Take 30 minutes before breakfast - food decreases absorption
Don't take antacids, calcium, or iron supplements withing 4 hours - Levothyroxine adverse effects
- Tachycardia, angina, tremor, HA, insomnia, diarrhea, voniting, cramps, weight loss, fatigue, excessive sweating
- Levothyroxine monitoring
- TSH every 6-8 weeks until normalized, then every 6-12 months
- Armour Thyroid Generic
- Desiccated thyroid Brand
- Cytomel/Triostat Generic
- Liothyronine Brand (T3)
- Thyrolar Generic
- Liotrix (T4 and T3 in 4:1 ration) Brand
- Hyperthyroidism Presentation
- Heat intolerance, weight loss, weakness
- Most common cause of hyperthyroidism
- Graves disease, Amiodarone and iodine also
- Hyperthyroidism diagnosis
- Elevated T4 or T3 and decreased TSH
- Hyperthyroid treatment methods
-
Surgery, radioactive iodine, antithyroid drugs
RAI treatment of choice in Graves' Disease
Propylthiouracil preferred in pregnancy - Thionamides (Methimazole and Propylthiouracil) MOA
-
Inhibit synthesis of thyroid hormones by preventing incorporation of iodine into iodotyrosines
PTU inhibits peripheral converson of T4 to T3 - Methimazole and PTU Adverse Effects
- Feer, headache, rash, arthralgia, jaundice, hepatitis