Hyperlipidemia
Terms
undefined, object
copy deck
- LDL Goal
-
CHD or equivalent (diabetes ) = <100
2+ risk factors = <130
0-1 risk factor = <160 - Total Cholesterol goal
- <200
- HDL
-
<40 low
>60 high - Triglycerides goal
- <150
- SEcondary causes of hyperlipidemia
-
diabetes
hypothyroidism
renal failure - Statins mechanism of action
- inhibit HMG-CoA reductase - inhiit cholesterol synthesis in liver
- Bile Acid Sequestrant MOA
- nonabsorbably anion exchange chloride ions for bile acits
- Statin Effects on lipids
-
decrease TC, LDL, TG
increase HDL - Bile Acids effects on lipids
-
Decrease TC, LDL
Slightly increase HDL - Fibrates effects on Lipids
-
Decrease Triglycerides*
Decrease LDL, increase HDL - Niacin effects on lipids
-
Decrease TG*
Decrease LDL, increase HDL - Fibrates Mechanism of action
- reduce triglycerides
- Zetia MOA
- inhibits intestinal absorption of dietary and biliary cholesterol
- STatins adverse effects
- headache, muscle aches, rhabdomyolysis, increased LFTs
- Bile Acids adverse effects
- GI upset, consipation
- Fibrates Adverse effects
- Dyspepsia, gallstones, myopathy
- Niacin Adverse effects
- Flushing, hyperglycemia, hyperuricemia
- Zetia adverse effects
- headache, ab pain, fatigue
- Lipitor Generic
- Atorvastatin Brand
- Lescol Generic
- Fluvastatin Brand
- Mevacor Generic
- Lovastatin Brand
- Pravachol generic
- Pravastatin brand
- Crestor Generic
- Rosuvastatin Brand
- Zocor Generic
- Simvastatin brand
- Tricor Generic
- Fenofibrate Brand
- Lopid Generic
- Gemfibrozil Brand