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Path buzzwords 301-350

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Term for speckled appearance of iris in Downs pts
Brushfield spots
Type of exudate from rickettsial infection
Hemorrhagic exudates
2 most common causes of epididymitis in males over 35
E Coli and Pseudomonas
Most common cardiac anomaly in kids
PDA
3 most common sites for left-sided heart embolisms to metastasize
Brain, spleen, kidney
Most common primary malignant tumor in bone
Osteosarcoma
Lucid interval
Epidural Hematoma
Pheochromocytoma rule of 10’s
10% bilateral, 10% malignant, 10% familial, 10% children, 10% outside adrenal gland
What tumor is seen in 2-4 yrs, does not cross midline, has immature glomeruli, tubules, and stroma, and metastasizes late to the lungs
Wilms tumor
Term for cytoplasmic remnants of RNA in RBCs, seen in lead poisoning
Basophilic stippling
What highly undifferentiated aggressive CNS tumor of primordial neuroglial origin develops in children and is associated with psudorosettes
Primitive neuroectodermal tumors (medulloblastomas and retinoblastomas)
What x-linked recessive disorder is due to an abnormality in dystrophin gene with onset by age 5 with progressive proximal muscle weakness, calf pseudohypertrophy, and elevated CPK levels
Duchenne muscular dystrophy
Most common cause of subacute bacterial endocarditis
Strep viridans
Decreasd plts, prolonged PT and PTT, decreased fibrinogen, and increased fibrin split products (D-dimers)
Disseminated intravascular coagulation (DIC)
What mineral deficiency involves blood vessel fragility
Copper
What are the 3 causes of normochromic, normocytic anemia with a normal MCV and a low retic count?
Marrow failure, cancer, and leukemia
2 lysosomal storage diseases with cherry-red spots on the retina
Niemann-Pick and Tay-Sachs
4 most common causes of femoral head necrosis
Steroids, Alcohol, Scuba diving, Sickle cell anemia
Most common childhood disease in US
Congenital heart failure
Type of Hypersensitivity Rxn: IgE-mediated release of chemical mediators from basophils and mast cells; need prior exposure to Ag in the past; eosinophils amplify and continue rxn; can be systemic or localized
Type I hypersensitivity (anaphylactic)
What form of vasculitis involves the ascending arch and causes obliterative endarteritis of the vasa vasorum
Syphilitic
Weeks to monthes after tx abrupt onset of oliguria and azotemia, seen as neutrophilic vasculitis and interstitial lymphocytes
Acute rejection
Most common Site of ischemia in GI tract
Splenic flexure
Type of exudate from diphtheria infection
Pseudomembranous exudates
Most common Tumor in men 15-35
Testicular tumors
Cancer associated with Ki-ras
Pancreas and colon
Keloid collagen type
Type III
Palpable, elevated solid mass up to 0.5 cm
Papule
What vitamin requires IF for absorption
Cyanocobalamin (B12)
Most common organism associated with liver abscesses
Entamoeba histolytica
Cancer associated with N-myc
Neuroblastoma
Malignant neoplasm of the bone associated with Homer-Wright pseudorosettes; onion skinning of the periosteum on x-rays of the femur, pelvis, and tibia, and chromosome 11;22 translocation
Ewing’s sarcoma
Acute promyelocytic leukemia (M3) chromosomal translocation
Chromosome 15,17
Glycogen storage disease due to deficiency of lysosomal glucosidase
Pompe’s disease
Type of exudate from uremic pericarditis
Fibrinous exudates
Avidin decreases absorption of what vitamin
Biotin
Most common Bladder tumor
Transitional cell carcinoma
What is the term for transverse bands on the fingernails seen in patients with chronic arsenic poisoning
Mees lines
Criteria for chronic bronchitis dx
3 months of productive cough in 2 consecutive years
Most common Liver tumor
Metastatic carcinoma
Cancer associated with Ki-ras and erb-2
Lung cancer
What bone cell has receptors for PTH
Osteoblasts (modulate fct of osteoclasts)
Most common Site for ectopic abdominal pregnancy
Rectouterine pouch (of Douglas)
Triad of fat embolism
Petechiae, Hyperactive mental status, Occurrence within 24-48 of initial insult
Most common cause of diarrhea in kids
Rotavirus
Two most common viral infections in HIV
CMV retinitis and HSV-2
Most common Type of hernias seen in males over 50
Direct
In which form of emphysema, panacinar or centriacinar, is the effect worse in the apical segments of the upper lobes
Centriacinar worse in upper lobes, panacinar worse in base of the lower lobes
3 Abs used to make SLE dx
ANA, anti-dsDNA, anti-Smith

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