KIT PHARMACACOLOGICAL TERMS
Terms
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- ANY CHEMICAL SUBSTANCE THAT HAS AN EFFECT ON LIVING TISSUE BUT IS NOT USED AS A FOOD
- DRUG
- RELIEVES SYMPTOMS OF DISEASE
- THERAPEUTIC
- PREVENT OR DECREASE SEVERITY OF DIESEASE
- PROPHYLACTIC
- THE SCIENCE OF DOSAGES
- POSOLOGY
- THE BRANCH OF PHARMACOLOGY THAT DEALS WITH THE SCIENTIFIC STUDY OF ABSORPTION, DISTRIBUTION AND EXCRETION (ADME)
- PHARMACOKINETICS
- THE PROCESS BY WHICH A SUBSTANCE IS TAKEN UP FROM THE SITE OF ADMINISTRATION THE SYSTEM
- ABSORPTION
- THE PROCESS OF MOVEMENT OF THE DRUG THROUGH THE BLOOD AND TRANSFER FROM THE BLOOD TO OTHER BODILY FLUIDS AND TISSUES
- DISTRUBUTION
- THE TRANSFORMATION OF THE DRUG BY PHYSIOLOGICAL PROCESSES OF THE BODY INTO OTHER FORMS, USUALLY LESS POTENT OR TOXIC THAN THE ORIGINAL FORM THAT CAN BE ELIMINATED
- METABOLISM
- THE STUDY OF DRUG ACTION ON LIVING ORGANISMS
- PHARMACODYNAMICS
- THE STUDY OF OF THE ECONOMIC ASPECTS OF DRUGS
- PHARMACOECONOMICS
- ANY CONDITION ACCOMPANYING OR RESULTING FROM A DISEASE, DISORDER OR OTHERABNORMALITY THAT PROVIDES EVIDENCE FOR ITS EXISTENCE
- SYMPTOMS
- A SET OF S/SX THAT OCCUR TOGETHER AND CHARACTERIZE A PARTICULAR DISEASE OR DISORDER
- SYNDROME
- LOCATION IN THE BODY WHERE THE DRUG EXERTS ITS EFFECT. INCLUDES LOCAL USE OR SYSTEMIC USE
- SITE OF ACTION
- REFERS TO THE SITE SPECIFIC APPLICATION OF DRUGS, SUCH AS AN ANALGESIC OINTMENT APPLIED TO A BURN
- LOCAL
- REFERS TO APPLICATION OF A DRUGBY MEANS OF ABSORPTION INTO THE BLOOD AND SUBSEQUENT TRANSPORTATION THROUGHOUT THE BODY
- SYSTEMIC
- HOW THE DRUG PRODUCES ITS EFFECTS IN THE BODY. INCLUDES AGONIST/ANTAGONIST EFFECT/NONSPECIFIC MEMBRANE LIPID INTERACTION/PROTEIN BINDING/OSMOTIC EFFECT
- MECHANISM OF ACTION
- LOCATION ON THE SURFACE OR WITHIN THE CELL THAT CONTAIN SPECIFIC PROTEIN MOLECULES THAT BIND TO OTHER SPECIFIC MOLECULES, PRODUCING SOME EFFECT IN THE CELL.
- RECEPTOR SITE
- A DRUG THAT BINDS TO PARTICULAR RECEPTOR SITE AND TRIGGERS THE CELLS RESPONSE IN A SIMILAR WAY TO THE BODY'S OWN CHEMICAL MESSENGER
- AGONIST
- A DRUG THAT BINDS TO A PARTICULAR RECEPTOR SITE AND BLOCKS THE ACTION OF THE ENDOGENOUS CHEMICAL MESSENGER WITHOUT TRIGGERING THE CELL'S RESPONSE.
- ANTAGONIST
- THE MAXIMUM THERAPEUTIC DOSE, ABOVE WHICH NO IMPROVED CLINICAL RESPONSE WILL OCCUR
- CEILING EFFECT
- THE LENGTH OF TIME A DRUG IS AT THERAPEUTIC CONCENTRATION LEVEL
- DURATION OF ACTION (DOA)
- THE TIME PERIOD REQUIRED AFTER ADMINISTRATION OF A DRUG TO ACHIEVE THE DESIRED RESPONSE, OR THERAPEUTIC CONCENTRATION LEVEL.
- ONSET OF ACTION
- THE DRUG DOSE THAT WILL PRODUCE A THERAPEUTIC RESPONSE IN 50 PERCENT OF THE POPULATION WHO RECEIVED THE DRUG
- EFFECTIVE DOSE 50
- THE DOSAGE THAT WILL KILL 50% OF THE POPULATION
- LETHAL DOSE 50
- UNUSUAL OR UNEXPECTED RESPONSE TO A DRUG. PECULIAR TO THE INDIVIDUAL AND SOMETIMES HAVE GENETIC CAUSES
- IDIOSYNCRASY
- A LOCAL OR GENERAL IMMUNE RESPONSE IN WHICH THE IMMUNE SYSTEM OVERREACTS TO AN OTHERWISE HARMLESS SUBSTANCE
- ALLERGY
- RESULTING IN IMMEDIATE LIFE THREATENING RESP DISTRESS, USUALLY FOLLOWED BY VASCULAR COLLAPSE AND SHOCK AND ACCOMPANIED BY HIVES
- SEVERE ALLERGIC REACTION
- LONGEST DIFFICULT NAME OF THE CHEMICAL MAKE UP THE DRUG AND RELATES TO THE CHEMICAL AND MOLECULAR STRUCTURE
- CHEMICAL NAME
- A SHORTENED VERSION OF THE CHEMICAL NAME THAT THE MANUFACTURER GIVES THE DRUG
- GENERIC NAME
- THE NAME UNDER WHICH THE MANUFACTURER HAS PATENTED THE DRUG
- TRADE/BRAND NAME
- THE BRANCH OF PHARMACOLOGY THAT DEALS WITH BIOLOGICAL, BIOCHEMICAL, AND ECONOMIC FEATURES OF NATURAL DRUGS AND THEIR CONSTITUENTS
- PHARMACOGNOSY
- PROVIDES STANDARDS FOR DRUGS OF THERAPEUTIC USEFULNESS AND PHARMACEUTICAL NECESSITY.
- US PHARMACOPEIA AND NATIONAL FORMULARY
- THE MOST WIDELY USED TEXT/REFERENCE IN AMERICAN PHARMACIES
- REMINGTON: THE SCIENCE AND PRACTICE OF PHARMACY
- THE THERAPEUTIC DOES IS CALCULATED ON AN AVERAGE ADULT
- 24 YEARS WHO WEIGHS 150 POUNDS
- DRUGS GROUPED ACCORDING TO THEIR SOURCE, WHETHER ANIMAL, VEGETABLE, OR MINERAL IN ORIGIN
- GENERAL
- DRUGS GROUPED BY THEIR CHEMICAL CHARACTERISTICS
- CHEMICAL
- DRUGS ARE GROUPED ACCORDING TO THEIR ACTION ON THE BODY
- THERAPEUTIC
- HISTAMINE H2 RECEPTOR ANTAGONISTS
- BLOCKS HISTAMINES THAT CAUSE AN INCREASE OF OF GASTRIC ACID SECRETION IN THE STOMACH. RELIEVES SYMPTOMS OF PEPTIC ULCERS
- EFFECTIVE AGAINST BOTH GRAM-POSITIVE AND GRAM-NEGATIVE ORGANISMS. WERE THE FIRST EFFECTIVE CHEMOTHERAPEUTIC AGENTS AVAILABLE
- SULFONAMIDES
- MOST EFFECTIVE AND LEAST TOXIC OF THE ANTIMICROBIAL AGENTS
- PCN