Opioid Analgesics
Terms
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- naloxone
- IV drug for treatment of opioid overdose
- Enkphalin
- Endogenous peptide; target is delta receptor
- Loperamide
- Diarrhea treatment; slows peristalsis of the GI tract
- Percodan
- Trade name for oxycodone + ASA
- Moderate
- Hydrocodone or oxycodone would be prescribed for this level of pain
- Opioids
- Class of centrally active anagelsics
- Perception of pain and emotional response
- Opioids block what two things.
- naltrexone
- Oral drug for treatment of opioid overdose
- Adenylate cyclase
- What specific protein does an opioid block?
- Demerol
- Trade name for Meperidine
- Dynorphin A
- Endogenous peptide; target is kappa receptor
- Cocaine, meperidine, morphine, oxycodone
- Four schedule 2 prescriptions
- Loperamide
- Active ingredient in immodium
- Tramadol
- Non-controlled substance Mu receptor agonist
- NSAIDs
- Class of peripherally active analgesic
- Lortab Vicodin
- Trade name for Hydrocodone (2)
- Moderate
- Codeine would be prescribed for this level of pain (WHO)
- Mu2
- Mu receptor subtype responsible for respiratory depression
- Oxycontin Roxicodone
- Trade name for Oxycodone (2)
- codeine
- Tylenol # 3 is which adjuvant of which opioid
- Duragesic Actiq
- Trade names for fentanyl (2)
- Talwin
- Trade name for Pentazocine (mixed agonist/antagonist)
- constipation
- GI side effect of loperamide (long term opioid use in general)
- Orudis KT
- Ketoprofen; substitute for opioids, formerly OTC
- Mild
- APAP would be prescribed for this level of pain
- Moderate
- Tramadol would be prescribed for this level of pain
- Mild
- ASA would be prescribed for this level of pain (WHO)
- B-endorphin
- Endogenous pain reducing peptide. Acts on Mu receptor
- Mu
- Major receptor site involved in opioid effectiveness. Found in CNS and GI tract.
- CYP450 2D6
- Degradation operant for opioids
- Secobarbital, codeine, hydrocodone
- Three schedule 3 prescriptions
- Substance P
- Neurotransmitter responsible for pain signal
- Propoxyphene, butorphanol, midazolam
- Three schedule 4 prescriptions
- Dilaudid
- Trade name for Hydromorophone
- Vicoprofen
- Trade name for hydrocodone + ibuprofen
- Severe
- Hydromorphone would be prescribed for this level of pain
- Severe
- Methadone would be prescribed for this level of pain
- Dextromethorphan
- OTC mu represor agonist; activate mu receptors in cough center of CNS
- Dolophine
- Trade name for Methadone
- Darvon
- Trade name for Propoxyphene