AUBiochem
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- Is catabolism an exergonic or endergonic process?
- Exergonic
- What is the product of glycogenolysis?
- glucose-1-phosphate
- What is formed by the direct phosphorylation of glucose by ATP?
- glucose-6-phosphate
- Where does glycolysis occur?
- in the cytoplasm
-
Which of the following cannot enter the glycolysis pathway?
glucose, fructose, galactose, or glycogen - glycogen
- Which coenzyme is use in most ox-red reactions of carbohydrate catabolism?
- NAD+/NADH
- What is the product of the endergonic stage of glycolysis?
- glyceraldehyde-3-phosphate
- How many net ATP come out of glycolysis per glucose molecule?
- 2 ATP net
- What is the final product of glycolysis?
- pyruvate
- What coenzyme must be reoxidized so that glycolysis can continue to produce energy?
- NADH
- To what does pyruvate convert under anaerobic conditions?
- lactate
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Under anaerobic conditions in a muscle cell, pyruvate is converted to which of the following:
ethanol, CO2 and H2O, acetyl-CoA - none of the above
- In the 1st stage of glycolysis, is the production of triose phosphates an exothermic or endothermic sequence of reactions?
- endothermic
- Where do oxidative (aerobic) reactions of metabolism occur?
- in the mitochondria
- What is the direct precursor for the citric acid cycle?
- acetyl-CoA
- Are glyceraldehyde-3-phosphate and dihydroxyacetonephosphate trioses, functional isomers, or monosacharides?
- They are all three.
- What are the (4) products of the tricarboxylic acid cycle?
-
- CO2
- 3 NADH
- 1 FADH2
- 1 GTP - Is gluconeogenesis the production of glucose from carbohydrate or non-carbohydrate sources?
- non-carbohydrate
- What is another name for the respiratory chain?
- the electron transport system (ETS)
- True of false? The electron transport system is found dispersed in the mitochondrial matrix?
- False
- What metal ions, present in the cytochromes of the ETS, aid in the passage of electrons down the chain?
- Fe 2+ and Fe 3+
- What is the final acceptor of electrons (H atoms) during respiration?
- O2
- What is the formation of ATP in the ETS called?
- oxidative phosphorylation
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True or false?
It is possible to oxidize the hydrogen atoms of acetySCoA w/o having oxidative phosphorylation occur? - True
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True or false?
Oxidative phosphorylation and electron transport are coupled in the ETS. - True
-
True or false?
Glycogenolysis directly leads to the formation of glucose-6-phosphate which undergoes glycolysis. - False
-
Which of the following is a product of the pentose phosphate pathway (shunt)?
NADH, NADPH, FADH2, FPH2 - NADPH
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Which of the following is a product of the pentose phosphate pathway (shunt)?
- ribose-5-phosphate
- fructose-1,6-diphosphate
- galactose-1-phosphate
- phosphoenolpyruvate (PEP) - ribose-5-phosphate
-
True or false?
NADPH is the coenzyme used in anabolic reactions (syntheses). - True
-
True or false?
The protein complex which is responsible for respiration is dispersed in the mitochondrial matrix. - False. The protein complex is dispersed in the mitochondrial membrane.
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True or false?
Before fats and oils can be metabolized, fatty acids must be released from triglycerides with the aid of a triacylglyceride lipase. - True
-
True of false?
The anabolism of fatty acids is called beta-oxidation. - False. Beta-oxidation is the catabolism of fatty acids.
- What is the activator/carrier molecule used in fatty acid catabolism?
- coenzyme-A, CoASH
- How many molecules of acetyl-CoA do you get from the complete beta-oxidation of a 12-carbon fatty acid?
- 6 molecules of acetyl-CoA
- Where does beta-oxidation occur?
- In the mitochondrial matrix
-
True of false?
Fatty acid synthesis is the complete reverse of beta-oxidation. - False
- What protein transports fatty acids through the inner mitochondrial membrane into the matrix?
- carnitine
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True of false?
The synthesis of a 12-carbon fatty acid is achieved by the sequential condensation of 6 acetyl-CoA molecules. -
False.
malonyl?? - Which coenzyme is the reducing agent used in fatty acid biosynthesis?
- NADPH
-
True of false?
The key intermediate in fatty acid synthesis is the free 3-carbon diacid malonate. - False
-
True or false?
Ketone bodies are formed when the concentration of acetyl-CoA in the cytoplasm is very high. - False
-
True or false?
In the cytoplasm, acetyl-CoA is used in the synthesis of non-saponifiable lipids. - True
- What is the activator/carrier molecule used in fatty acid oxidations?
- CoASH
-
Which of the following is a ketone body?
- acetyl-CoA
- acetone
- malonate
- malonyl-CoA - Acetone is a ketone body.
- What is the most important function of amino acids?
- Synthesis of proteins
- What are the two key amino acids in the catabolism of the amino group of amino acids?
- glutamate and aspartate
- What is the direct result of oxidative deamination of amino acids?
- ammonium ion
- What is the direct "fuel" for the urea cycle?
- carbamoyl phosphate
- What is the term for the production of glutamate from alpha-ketoglutarate?
- transamination
-
True or false?
Oxaloacetate is the molecule which reacts with carbamoyl phosphate at the start of the urea cycle. - False
- What is the second amino group of urea derived from?
- aspartate
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True of false?
Glycogenolysis is the cleavage of glucose-1-phosphate from the ends of glycogen molecules. - False
-
Which of the following can enter the glycolysis pathway?
- glucose
- fructose
- galactose - All of the above
- What is the product of the 1st stage of glycolysis?
- glyceraldehyde-3-phospate
- Under aerobic conditions in the body, pyruvate is converted to what?
- acetyl-CoA
-
True of false?
The production of triose phosphates in the 1st stage of glycolysis is an endothermic sequence of reactions. - True
- How many molecules of CO2 are produced in one Kreb's cycle?
- 2 molecules of CO2
- What is the net yield of ATP from the complete catabolism of one molecule of glucose?
- 36 net ATP
-
The majority of the ATP produced during the catabolism of glucose is formed during which process?
- oxidative phosphorylation
- glycolysis
- Kreb's cycle
- glycogenolysis - oxidative phosphorylation
- What percentage of the energy available from glucose catabolism is trapped in the formation of ATP?
- 40%
-
True of false?
Before fats and oils can be metabolized, fatty acids must be released from triglycerides. - True
- What is the catabolism of fatty acids called?
- beta-oxidation
-
True or false?
Acetyl-CoA is used in the synthesis of steroids in the cytoplasm. - True
- What is the activator/carrier molecule used in fatty acid biosynthesis?
- ACP
-
True or false?
Carbamoyl phosphate is produced by the reaction of CO2, ammonium ion, and ATP. - True
- What is an anaplerotic reaction?
- A reaction that replenishes a substrate needed for a biochemical pathway.
- What is an amphibolic pathway?
- A pathway that is both anabolic and catabolic