Drugs - Antineoplastics
Terms
undefined, object
copy deck
- What do antineoplastic agents do?
- inhibit the new growth of cancer cells, neoplasms
- What is meant by metastisized?
- when the original cell group spreads to other areas
- What are lymphocytes and what do they do?
- a type of white blood cell that releases antibodies that attack and destroy antigens
- What are the 2 primary types of lymphocytes?
- T-cells and B-cells
- Maintainence of the body's lymphocyte supply is largely performed by what?
- the bone marrow
- What type of cells do antineoplastic drugs target?
- cells with fast growth rates
- How do antimetabolites work?
- they inhibit cell growth and replication by mimicking natural metabolites and taking their place within the cells; they inhibit the synthesis of cellular enzymes
- How do alkyating agents work?
- they interfere with mitosis, cell division, by binding with DNA and preventing cellular replication
- What are nitrogen mustard gases known to do?
- inhibit cellular growth and sperm counts while depressing bone marrow and damaging intestinal mucosa
- What are nitrosureas and how do they work?
- an alkyating agent that is lipid soluble and passes easily into the brain where they can treat brain cancers
- What are some rapidly replicating cells in the body that can be affected by antineoplastics?
- those of the GI tract, bone marrow, and hair follicles
- What is Topoisomerase?
- required for molecular cell growth, mitosis
- What type of drug is Cyclophosphamide?
- a neoplastic alkylating agent
- What type of drug is Cisplatin?
- an antineoplastic drug
- What type of drug is Busulfan?
- a neoplastic alkylating agent
- What type of drug is Methotrexate?
- a neoplastic antimetabolite
- What type of drug is 5-Fluorouracil?
- a neoplastic antimetabolite
- What type of drug is Mercaptopurine?
- a neoplastic antimetabolite
- What type of drug is Vincristine?
- a neoplastic plant alkaloid
- What type of drug is Paclitaxel?
- a neoplastic plant alkaloid
- What type of drug is Etoposide?
- a neoplastic plant alkaloid
- What type of drug is Tamoxifen Citrate?
- a neoplastic anti-estrogen
- What is the brand name for Busulfan?
- Myleran
- What is the generic name for Myleran?
- Busulfan
- What is the brand name for Etoposide?
- Vepesid
- What is the generic name for Vepesid?
- Etoposide
- What type of drug would have the stem -arabine in the word?
- an antineoplastic drug
- What type of drug contains the stem -mustine in the name?
- antineoplastics
- What type of drug contains the stem -rubicin in the name?
- antineoplastics