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blood

92% 25 terms 11/11/08

Terms

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red blood cells
normal span of life 120 days. Destroyed in spleen.
lymphocytes
25-33%, the two types of white blood cells that are part of the body's immune system: B lymphocytes form in the bone arrow and release antibodies that fight bacterial infections; T lymphocytes form in the thymus and, among other duties, attack cancer cells, viruses, and foreign substances
White blood cells
known as leukocytes. Have a nuclei and are produced in bone marrow.
basophils
Inflammation mediators, immediate allergic reactions, Blood cells that enter damaged tissues and enhance the inflammation process and contain histamine and heparin
neutrophils
60% of WBC, function is for phagocytosis...it is a major component of our second line of defense. they are the first to arrive at an infection to eat debris and microbes
hemoglobin
destroyed as bilirubin,normal content in blood is 14.5 gm/100 cc of blood
MCD
7.2 micron
red blood cells
circular, biconcave, disc shaped and non nucleated cells. Composed of globin (protein), iron (metal), phospholipid (lipid) and potassium phosphate (salt)
granulocytes
a group of leukocytes containing granules in their cytoplasm.neutrophils, eosinophils, basophils
MCHC
measure of hemoglobin per 100cc of blood.31 to 37
MCH
measure of hemoglobin per RBC. 26 to 34
agranulocytes
lymphocytes, monocytes/macrophages, a group of leukocytes without granules in their nuclei
G6PD
glucose-6-phosphate dehydrogenase. necessary to maintain glutathione level (GSH) through NADPH and thus prevent hemolysis.Deficiency causes severe hemolytic anemia with concomitant use of oxidants: primaquine,sulfonamide, nitrofuran, nalixidic acid, probenecid, chloroquine and dimercaptol. Sicke cell anemia or Bethalassemia.
monocytes
an agranulocytic leukocyte that performs phagocytosis to fight infection, transform into macrophages that engulf large #s of microbes over a long period of time
Rh factor
child + and mother - may be fatal for children
serum
blood plasma without clotting proteins
Glutathione
antioxidant that prevents ox. of hemoglobin to methemoglobin.When RBS is deficient in G6PD, NADPH not enough to keep glutathione in reduced state, free radicals accumate and oxide hemoglobin. , Acetaminophen toxicity is combated with...
platelets
thrombocytes, process of clotting, no nuclei.platelets adhere-thromboplastin is liberated and convert prothrombin into thrombin-Thrombin converts fibrinogen to fibrin-patchwork and clot.
MCV
volume of individual RBC per cubic micron. 80 to 100
erythropoiesis
formation of RBC. Hemocytoblast-Megaloblast-Early erythroblast-Late erythroblast-Normoblast-Reticulocytes-Erythrocytes.
hyperchromic anemia
defective RBC formation. RBC is large. Also known as megaloblastic anemia. Caused by deficiency of Vit B12 or Folic acid.Pernicious anemia.
diagnosis of anemia
Color Index, MCHC,MCD,MCV,MCH
eosinophils
What chronic inflammatory WBC is associated with IgE-mediated allergic reactions and parasitic infections?
Color index
0.85 to 1.15. Relative amount of hemoglobin present in the single RBC.
hypochromic anemia
reduced amount of hemoglobin in the RBC. Also known as iron deficiency anemia.RBC are small.Described also as microcytic anemia.

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