Soft Tissue Lesions
Terms
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- Reactive lesion, or 'true' neoplasia? Overgrowth is in response to irritation
- Reactive lesion
- Reactive lesion, or 'true' neoplasia? Associated with a stimulus
- Reactive lesion
- Reactive lesion, or 'true' neoplasia? Usually inflammation a consistent finding
- Reactive lesion
- Reactive lesion, or 'true' neoplasia? Growth continues after stimulus is removed/no stimulus required
- 'true' neoplasia
- Reactive lesion, or 'true' neoplasia? No regression with normal therapy
- 'true' neoplasia
- Reactive lesion, or 'true' neoplasia? Unrestricted new growth
- 'true' neoplasia
- What is the most common 'tumor'/lesion in the oral cavity?
- Irritation fibroma
- Where is the most common location to find an irritation fibroma?
- Buccal mucosa, at the occlusal plane
- What age group and gender is most often affected by irritation fibromas?
- 40-60 year old females
- What two colors are irritation fibromas (usually)?
- 1 Pink (same shade as mucosa) 2 White from hyperkeratosis
- Name 3 histological findings in irritation fibromas.
- 1 Dense CT 2 Inflammatory cells 3 Stratified squamous epithelium
- What is the term used for an irritation fibroma caused by a denture?
- Epulis Fissuratum
- What characterizes Epulis Fissuratum?
- Long folds of dense CT
- Name 3 common causes for papillary hyperplasia.
- 1 Ill-fitting dentures 2 Dentures worn 24 hours/day 3 Poor denture hygiene
- What clinical feature is pathognomonic for Epulis Fissuratum?
- Raspberry, bubbly, papillary look, usually on hard palate
- What microorganism is often to blame for Epulis Fissuratum?
- Candida
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? Usually on gingiva, but occur anywhere
- Pyogenic granuloma
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? Bright red color
- Pyogenic granuloma OR ulcerated peripheral fibroma
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? Bleeds easily
- Pyogenic granuloma
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? Painless
- Pyogenic granuloma and peripheral giant cell granuloma for sure
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? Caused by irritation
- All three
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? Develops rapidly
- Pyogenic granuloma
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? More common in children and young adults
- Pyogenic granuloma and peripheral fibroma
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? Found in pregnant women
- Pyogenic granuloma
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? Female predilection
- All three
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? Histologically has endothelial lined vascular spaces
- Pyogenic granuloma
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? Most common of the three
- Pyogenic granuloma
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? Bluish-purple in color
- Peripheral Giant Cell Granuloma
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? Pink color
- peripheral fibroma OR Peripheral Giant Cell Granuloma
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? Affects individuals around age 30
- Peripheral Giant Cell Granuloma
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? Can only occur on the gingiva
- Peripheral Giant Cell Granuloma or Peripheral fibroma
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? Histologically has CT stroma, mesenchymal cells, and multinucleated giant cells
- Peripheral Giant Cell Granuloma
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? Results from pyogenic granuloma developing over time
- Peripheral fibroma
- Pyogenic granuloma, peripheral giant cell granuloma, or peripheral fibroma (or more than one)? Histologically has dense CT with mineralization (calcified or ossified)
- Peripheral (ossifying) fibroma
- What term is used for red vascular tissue growing out of recent extraction site or socket?
- Epulis Granulomatosa
- Name the most common oral area to have a lipoma.
- Buccal mucosa
- What color is a lipoma?
- Yellowish
- What kind of cells are subject to neurolemoma?
- Schwann cells (it's also called a schwannoma)
- Are neurolemomas fast or slow-growing?
- Slow-growing
- Name the most common oral area to have a neurolemoma.
- Tongue
- What soft tissue lesion is associated with Antoni A and B tissue types?
- Neurolemoma (Schwannoma)
- What soft tissue lesion is associated with Verocay bodies?
- Neurolemoma (Schwannoma)
- Name the most common peripheral nerve neoplasm, which is rare but not uncommon.
- Neurofibroma
- What soft tissue lesion is associated with spindle cells, and Mast cells intermingled with neurites?
- Neurofibroma
- Name the hereditary/systemic form of neurofibromas.
- Von Recklinghausen's Disease of the Skin
- Name two clinical features of Von Recklinghausen's Disease of the Skin.
- 1 Multiple neurofibromas 2 Café au lait spots
- What 'neoplasm' occurs when a damaged nerve attempts to repair itself?
- Traumatic neuroma
- Is a Traumatic neuroma painless or painful?
- Painful
- What lesion has the following histology: Neurofibrils and Schwann cells in CT?
- Traumatic neuroma
- What is the most common tumor of infancy?
- Hemangioma
- What causes a hemangioma?
- Proliferation of blood vessels
- What color is a hemangioma?
- Deep blue (this helps diagnose)
- If a hemangioma is present as a large, flat lesion of the skin, what term is used?
- Birthmark
- If a hemangioma is present as a large, unilateral lesion on the face following the division of the trigeminal nerve, what term is used?
- Port-wine stain
- What type of biopsy must be done on a hemangioma: Incisional or excisional?
- Excisional, because it bleeds profusely with incisional
- What is "diascopy"?
- Blanching with pressure
- A hemangioma (does/does not) blanch with pressure.
- DOES
- If a hemangioma is present due to small capillary proliferation, what disease is this?
- Hereditary Hemorrhagic Telangiectasia (Osler-Weber-Rendu)
- What disease features Port-wine stian, and maybe convulsive disorders and mental retardation due to calcifications in the brain?
- Sturge-Weber Syndrome
- What is more common, hemangioma or lymphangioma?
- Hemangioma
- How can you differentiate a lymphangioma from a hemangioma?
- Lymphangiomas are pink, or colorless, not red.
- If a lymphangioma is present in the tongue, what syndrome could occur secondarily?
- Macroglossia
- Name the most common oral area to have a granular cell tumor.
- Tongue
- What lesion has the following histology: Large, granular cells with eosinophils, keratin production, and pseudoepitheliomatous hyperplasia?
- Granular cell tumor
- What soft tissue lesion may be confused with carcinoma?
- Granular cell tumor
- What disease features fibroma-looking lesion at birth?
- Congenital Granular Cell Epulis
- Where is the most common location to find a Congenital Granular Cell Epulis?
- Maxillary anterior gingiva
- T/F: Congenital Granular Cell Epulis most commonly affects males.
- False; the predilection is 90% female, suggesting a hormonal link
- What disease features rapidly-growing dark, pigmented lesion at birth?
- Melanotic Neuroectodermal Tumor of infancy
- What disease is associated with high levels of vanilmadelic acid in the urine?
- Melanotic Neuroectodermal Tumor of infancy
- What lesion has the following histology: Mass of cells arranged in a pattern of alveolus-like spaces, lined by cuboidal cells, maybe containing melanin?
- Melanotic Neuroectodermal Tumor of infancy