Synaptic transmission 2
Terms
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- Current
- movement of net positive charges from an anode (+) to cathode (-)
- Potassium (K) concentration
- inside cells 125, outside cells 5
- Sodium concentration (Na)
- inside cells 10, outside cells 122
- Chloride (Cl) concentration
- inside cells 5, outside 125
- Calcium concentration
- inside 0.0001, outside 2
- Large anions concentration
- inside 130, outside 0
- Cation
- positively charged particle (accumulates on the negative pole or cathode of a battery)
- Anion
- negatively charged particle (accumulates on positive or anode of a battery)
- Capacitor
- two conducting materials separated by an insulating material, capacitance measured in farads
- Which ion can flow across resting membrane
- K
- Equilibrium potential for K
- -80 mV
- Equilibrium potential for Na
- 60 mV
- Equilibrium potential for Ca
- 120 mV
- What is voltage and how is it generated and measured?
- voltage is the difference in charge between anode and cathode, also called the force exerted on a charged particle, measured in volts.
- Na/K ATPase
- large membrane spanning protein wiht binding sites for Na, K, ATP, extrudes 3 Na + ions for every 2K+ ions it pumps inside the cell
- 2 mechanisms of Na channel inactivation
- ball and chain and c type inactivation