USMLE Mixed Batch
Terms
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- Carotid baro-receptors are pressure receptors in the wall of the carotid that?
- i) detect increases in blood pressure and signal the vasomotor center to reduce blood pressure via activation of the parasympathetic system and ii) detect decreases in blood pressure and signal the vasomotor center to increase blood pressure via activation of the sympathetic system.
- Major function of α1?
- Increase vascular smooth muscle contraction
- Major function of β1?
- increase heart rate, increase contractility, increase renin release, increase lipolysis, increase aqueous humor formation
- Major function of α2?
- decrease sympathetic outflow, decrease insulin release
- Major function of β2?
- vasodilation of arteries to muslces, bronchodilation, increase glucagon release in CNS
- Major function of M2?
- decrease heart rate
- Major function of M3?
- increase exocrine gland secretions
- Major function of D1?
- Relaxes renal vascular smooth muscle
- Major function of D2?
- Modulates transmitter release, especially in brain
- Major function of H1?
- increase nasal and bronchial mucous production, contraction of bronchioles, pruritis, and pain
- Major function of H2?
- increase gastric acid secretion
- Activation of this Gq protein class receptor leads to increased?
- phospholipase C--Lipids split to PIP2--Split to IP3 and DAG leading to increased Calcium and Protein C
- Activation of this Gs protein class receptor leads to increased?
- Andenylcyclase leading to increased cAMP and thus increased protein kinase A
- Activation of this Gi protein class receptor leads to increased?
- Andenylcyclase leading to decreased cAMP and thus decreased protein kinase A
- Name the receptors that use Gq (4), Gs (4), Gi(3) resepectively?
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Gq (α1,M1, M3, H1)
Gs (β1,β2, D1, H2,)
Gi (α2, M2, D2)