Microbiology Immune Response
Terms
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- acquired immunity
- immunity that develops from exposure to an antigen
-
key properties of
acquired immunity - specificity and memory
-
antigenic determinant /
epitope - specific molecular groups to which an antibody reacts
- antigen / immunogen
-
any substance that reacts with products of an immune response /
immunogen stimulates the response -
antigen-presenting cell
APC - A cell that presents peptide fragments associated with MHC class II proteins
- protein receptor
- membrane bound proteins on the surface of cells that recognize specific antigenic determinants
- MHC
-
major histocompatability complex
cell surface proteins for self-recognition and immune responses - humoral response
- protective response mediated by antibody molecules that circulate with the body fluids
- cell-mediated response
- protective response mediated by specialized cells
- immunity
- all of the mechanisms used by the body as protection against microorganisms and othe foreign agents
-
nonspecific external
defense mechanisms -
First line of defense
includes physical barriers, chemical agents and bacterial interference -
nonspecific internal
defense mechanisms (5) -
Second line of defense
phagocytosis
lymphatic system
inflammation
white blood cells and
other blood components - Protective physical barriers (7)
-
Skin
Mucous membranes
eyes (lysozyme)
outer ear canal
alimentary canal
genitourinary tract
respiratory tract - White blood cells
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Granulocytes (neutrophils / basophils)
Monocytes (macrophages)
Lymphocytes (B cells / T cells) - Neutrophils
-
WBC 1% of body weight
1st of acute inflammatory response
phagocytize bacteria - Macrophages
-
wandering and fixed
- phagocytic
- present antigen to lymphocytes - B cells
-
lymphocytes found in lymph nodes and spleen
preprogrammed to respond to a specific antigen - T cells
-
lymphocytes found in thymus
respond to specific antigens that have been presented to them