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Cardiovascular system:blood chapter 14

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Describe blood according to its tissue type
Blood is a connective tissue whose cells are suspended in liquid called plasma.
Describe major function of blood.
Functions of blood include transporting substances between body cells and the outside, maintaining homeostasis and protection.
Define the term hematology
Hematology is the study of blood, blood-forming tissues and the disorders that affect them.
Name the average volume of blood in a human.
Blood volume varies from individual to individual, but the average volume (70 kg male) is 5 liters.
Name the two major components of blood and the percentage of each by weight.
Solid cells or "formed elements" (45%), which is composed mainly of red blood cells.



a. Quantitation of this portion of blood represents the hematocrit (HCT) reading or packed cell volume (PCV).





Liquid plasma (55%), which contains water, electrolytes, hormones, wastes, proteins and much more
Name the three types of human blood cells
red blood cells, white blood cells, and platelets
Provide the common and scientific name for each blood cell type.
Red Blood Cells (RBC) = Erythrocytes

White Blood Cells (WBC) = Leukocytes

Platelets = thrombocytes
Hemoglobin
Hemoglobin is broken into globin and heme,

Iron in Hb is recycled,

Heme is broken into biliverdin > bilirubin > bile.
Why do mature cells lack nuclei?
are anucleate, leaving more room for hemoglobin/oxygen;
RBC Count
The number of rbc's/mm3 blood.
Average RCC = 4 million-6 million rbc's/mm3
Average life-span of RBC's
120 days
What destroys RBC's
Liver and spleen macrophages destroy worn rbc's
Production (Erythropoiesis) of RBC's
In fetuses = yolk sac, liver, spleen;

In adults = red bone marrow;

B12, folic acid, and iron are all needed.

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