AIDS
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- What are the 2 diagnostic criteria of AIDS?
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A. No known cause of immuno- suppression (cancer, steroids, renal failure)
B. Has disease predictive of a defective cellular immune function. - When can AIDS be diagnosed?
- When a previously healthy patient under 60 yrs meets both criteria A and B.
- What is the Etiologic agent of AIDS?
- Human Immunodeficiency Virus
- What are 2 other names for HIV?
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HTLV-III
LAV - What is the highest risk group for AIDS? What are 4 others?
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Homosexuals or Bi
IV drug users, Hemophiliacs, Haitians, others. - What 2 parameters measure Aids?
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-Viral load
-Tcell counts - What are the 2 categories of immune system changes in AIDS?
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1. Cellular
2. Humoral - Name 3 cellular changes that take place in AIDS:
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1. Delayed hypersensitivity skin test anergy
2. Lymphopenic - low T cells
3. Decreased Th:Tc ratio - What are the 3 characteristic Humoral indications of aids?
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1. Normal B cells
2. Increased IgG and IgA
3. Elevated circulating Ig's - What is the standard HIV screening test?
- ELISA for HIV antibody
- What test confirms a positive HIV Screen?
- Western blot
- what is the purpose of the western blot for AIDS?
- to see if the elisa reactivity corresponds to viral proteins of specific molecular weight.