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Microbiology Chap.26

Terms

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Minor changes in antigens due to gene mutation in influenza virus
antigenic drift
Major changes in antigens due to gene reassortment in influenza virus
antigenic shift
Breakdown of the normal liver architecture resulting in fibrosis
cirrhosis
A synthetic polypeptide that binds to viral glycoproteins, inhibiting fusion of viral and host cell membranes
fusion inhibitor
A liver inflammation commonly caused by an infectious agent
hepatitis
The production and release of excess bilirubin in the liver due to destruction of liver cells, resulting in yellowing of the skin and whites of the eye
jaundice
Inflammation of the meninges (brain tissue), sometimes caused by Neisseria meningitidis and characterized by sudden onset of headache, vomiting, and stiff neck, often progressing to coma within hours
meningitis
A fulminant disease caused by Neisseria meningitidis and characterized by septicemia, intravascular coagulation, and shock
meningococcemia
A nonnucleoside compound that inhibits the action of viral reverse transcriptase by binding directly to the catalytic site
nonnucleoside reverse transcriptase inhibitor (NNRTI)
A nucleoside analog compound that inhibits the action of viral reverse transcriptase by competing with nucleosides
nucleoside reverse transcriptase inhibitor (NRTI)
An infection usually observed only in an individual with a dysfunctional immune system
opportunistic infection
A compound that inhibits the action of viral protease by binding directly to the catalytic site, preventing viral protein processing
protease inhibitor
An inflammatory autoimmune disease triggered by an immune response to infection by Streptococcus pyogenes
rheumatic fever
A characteristic reddish rash resulting from an exotoxin produced by Streptococcus pyogenes
scarlet fever
An infection that is usually transmitted by sexual contact
sexually transmitted infection (STI)
Acute systemic shock resulting from a host response to an exotoxin produced by Staphylococcus aureus
toxic shock syndrome (TSS)
A skin test for previous infection with Mycobacterium tuberculosis
tuberculin test
A quantitative assessment of the amount of virus in a host organism, usually in the blood
viral load

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