A&P 122
Terms
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- P.N- what is Jaundice?
- an excess bile pigments (billiverdin-green & b. rubin-yellow/orange) accumulate in the blood- it yellows the sclera, skin and nails
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Pathology
(Factors affecting Erythropoiesis) - e.g., Blood loss, lung disease
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B Complex Vitamins
(Factors affecting Erythropoiesis) - B12 & folic acid req. for DNA synthesis & producing Erythropoiesis
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Minerals
(Factors affecting Erythropoiesis) - Fe is req. for hemoglobin synthesis
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pregnancy
(Factors affecting Erythropoiesis) - blood vol. Inc, during pregnancy due to H2) retention but hematocrit decreases. Imbalance corrected by erythropoiesis.
- Characteristics of Leukocytes (WBC's)
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1. nucleated
2. capable of leaving circulatory system
3. 2x size of RBC in mammals
4. formed in red marrow
5. life span of WBC is 12hrs w/ exception of lymphocytes
6. comprise less than 1% of Pack cell volume
7. fight disease
8.Transported in circ. system -
Types of WBC's
Classified based upon: -
a. nuclear size and shape
b. size.
c. granulation of the cytoplasm -
(Granulocytes)
Neutrophils (f) - F: phagocytize bacteria, fungi and some viruses
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(Granulocytes)
Eosinophils (f) - f: moderate allergic reactions, fight parasitic worms (1-3% of WBC's)
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(Granulocytes)
Basophils (f) - f: travels to damaged tissue and releases histamine and heparin (prevents clotting)
- Heparin dilates capillaries & Inc. permeability allowing;
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a)inc. blood flow to area
b)fluids to swell tissues (edema) reducing movement of pathogens through tissues. -
(Agranulocytes-no cytoplasmic grains)
-Monocytes (f) - f; mature into macrophages that phagocytize bacteria, dead cells, and debris. (3-9% of WBC's)
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(Agranulocytes-no cytoplasmic grains)
-Lymphocytes -
Two major forms (25-33% of WBC's)
f: T CElls and B cells - T Cells (f):
- directly attack; tumor cells, foreign cells, some microorganisms
- B cells (function)
- Produce antibodies (gamma globulin proteins) that attack; foreign cells and foreign proteins