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Unit4

Terms

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One of the main mechanisms for the production of inflammation & pain
Arachidonic Acid Pathway
Lidocaine is part of what class of local anesthetics
amides
____-acting Benzo's cause the Hangover effect
Long
Fentanyl (Sublimase) is an
IV General Anesthetic
Olanzipine (Zyprexa)
ATypical Anti-Psychotic
NSAIDs & Salicylates inhibit which enzyme in the pathway of PG synthesis
COX-2
Benzo's MOA
Increase the activity of GABA
The most serious potential SE of narcotics
respiratory depression
Temazepam (Restoril) is what type of Benzo
Short Acting
Drinking Alcohol with NSAIDs & Salicylates can increase the possibility of
ulcers
Prilocaine (Citanest) is pt. of what class of local anesthetics
amides
Seizures are the
uncontrolled discharge of neurons in the brain
Clozapine (Clozaril)
ATypical Anti-Psychotic
Anti-Virals MOA
increase DA
Darvocet N-100
propoxyphene/APAP
direct injury to nerves
Neuropathic pain
EPS includes (4)
dystonic reactions, akathisia, parkinsonism, & tardive dyskinesia
The primary MOA of anti-parkinson drugs is to
increase DA & decrease ACH
Fiorinal
ASA/caffeine/butalbital
Haloperidol (Haldon)
Typical Anti-Psychotic
Primadone (Mysoline)
Barbituate
The 4 Types of Seizures
Partial Complex, Grand Mal, Status Epilepticus, & Petit Mal
Benzo's are used for what 3 things
Seizures, Sedative/Hypnotics, & Anxiety
Midazolam (Versed) is an
IV General Anesthetic
Diazepam (Valium) is an
IV General Anesthetic
Divalproex Sodium (Depakote)
Anti-Epileptic (Misc.)
Bromocription (Parlodel)
DA Agonist (increases DA)
Tonic Convulsions last ~
2-10mins
Halothane (Fluothane) is an
Inhaled General Anesthetic
The benefit to ATypical Anti-Psychotics
rarely produce EPS SEs
DOC for Status Epilepticus
Valium (diazepam)
Narcotics (Opiods) work at which level
CNS
Symmetrel (Amantadine)
Anti-Viral
Thiothixene (Navane)
Typical Anti-Psychotic
Parkinsonism
find hand tremors
Sinemets MOA
(Levodopa + Caridopa) increases DA to higher levels
Gabapentin (Neurontin)
Anti-Epileptic (Misc.)
Divalproex Sodium (Depakote) SEs
irregular menses, hair loss, galactorrhea
Tylenol antidote
acetylcysteine
Selegeline (Eldepryl)
DA Conserver (keeps DA from getting lost)
Pain to tissues
Nociceptor pain
Symptoms of PD
resting tremors, cogwheel muscular ridgity, sweating, salivation, bradykinesia
Epilepsy is the
condition resulting from reoccuring seizures
Anti-Cholinergics MOA (PD)
decrease ACH
Ultram (Tramadol)
combination analgesic (narcotic)
Piroxicam (Feldene)
NSAID
Dystonic Reactions
involuntary muscle twitch or spasms
Akathisia
pacing, fidgeting, restlessness
Molindone (Moban)
Typical Anti-Psychotic
benzocaine (solarcaine) is pt. of which class of local anesthetics
esters
NSAIDs MOA
Inhibit the pathway of prostaglandin synthesis
Valproic Acid (Depakene)
Anti-Epileptic (Misc.)
Disadvantages to Buspar
Have to take continually, Has no anti-convulsant/skeletal muscle relaxant properties, Has slow onset of action
Insoflurane (Forane) is an
inhaled general anesthetic
Buspars full therapeutic effect takes ____
3-4 weeks
Signs of an Aura
Nausea, smelling an unpleasant odor, numbness, visual disturbances, dizziness
If experiencing Aspirin toxicity, administer (3)
Sodium Bicarbonate, fluid, & electrolytes
Barbituates are used for what 3 things
Seizures, Sedative/Hypnotics, & Pre-anesthetic
Anti-Epileptics MOA
decrease CNS activity
4 Drugs That treat Seizures
Hydantoins, Benzodiazepines, Barbituates, & Misc.
Chlorpromazine (Thorazine)
Typical Anti-Psychotic
Somatic pain
sharp, localized sensations
Visceral Pain
generalized dull, throbbing, or aching pain
Chloral hydrate
nonbarbituate
(6) Drugs that treat Parkinsons Disease
Levodopa, Anti-Histamines, Anti-Cholinergics, Anti-Virals, DA Agonists, & DA Conservers
PD is a
progressive disorder of the basal ganglia
Drugs used to treat Anxiety
Benzodiazepines & Buspar
Anti-Psychotic DOC
Zyprexa (Olanzapine - b/c rarely causes agranulocytosis)
Motrin/Advil
NSAID
Parkinsons Disease involves what imbalance of NTs?
decrease in DA & increase in ACH
Tylenol w/ Codeine
APAP/Codeine
Advantages to Buspar
No abuse potential, No sedation, Not effected by alcohol
Pimozide (Orap)
Typical Anti-Psychotic
Zaleplon (Sonata)
Nonbenzodiazepine
Drinking Alcohol with Tylenol can increase the possibility of
Hepatotoxicity
Procaine (Novocaine) is pt. of what class of local anesthetics
esters
Tardive Dykinesia
involuntary movement of extremeties, jaw, tongue
EPS results from an
increase in ACH
Triazolam (Halcion) is what type of Benzo
Short Acting
Flurazepam (Dalmane) is what type of Benzo
Long Acting
Zolpidem (Ambien)
Nonbenzodiazepine
the 3 classes of IV anesthetics
Barbituates, Opioids, & Benzodiazepines
Vicodin
Hydrocodone/APAP
Anti-Psychotics SEs include
Sedation, Anti-Cholinergic effects, orthostatic hypotension, EPS
4 Specific Areas depressed by Benzo's
Reticular Formation, Limbic System, Cerebral Cortex&Medulla, &Spinal Cord
Salicylates MOA
Inhibit prostaglandin synthesis
Non-Narcotics work at which level
peripheral
Keppra (levetiracetam)
Anti-Epileptic (Misc.)
Fioricet
APAP/caffeine/butalbital
Clonazepam (Klonopin) is what type of Benzo
Long Acting
Anxiety causes and increase in our
Sympathetic System
The uncontrolled neuron discharge occurs in the
cerebral cortex
Lamictal (lamotrigine)
Anti-Epileptic (Misc.)
Diazepam (Valium) is what type of Benzo
Long Acting
Lorazepam (Ativan) is what type of Benzo
Short Acting
Aspirin SEs (4)
tinnitus, respiratory depression, acidosis, & Reyes Syndrome
Narcotics supress the
cough reflex
our Limbic System deals with
emotional & behavior responses
Loxapine (Loxitane)
Typical Anti-Psychotic
Anti-cholinergics MOA
decrease ACH which decrease EPS SEs
Reticular Formation deals with
alertness & wakefulness
Pentothal (thiopental sodium) is what type of anesthetic
IV General Anesthetic
Avoid ___ w/ all Analgesics
Alcohol
Which Inhaled general anesthetic is the most commonly used due to less SEs?
Forane (Insoflurane)
Alprazolam (Xanax) is what type of Benzo
Short Acting
Our Spinal Cord controls
skeletal muscle activity
Status Epilepticus Convulsions last ~
30mins
Anti-Histamines MOA (PD)
decrease ACH
An Aura is present in all seizures except
Petit Mal Seizures
Promethazine (Phenergan)
Typical Anti-Psychotic
Thiopental Sodium (Pentothal) is an
IV General Anesthetic
Thioridazine (Mellaril)
Typical Anti-Psychotic
Gabitril (tiagabine)
Anti-Epileptic (Misc.)

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