Immune disorders 2
Terms
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- transplant prefixes/suffixes
-
auto: self graft
iso: between isogenetic individuals (genetic ‘identical’ twins)
allo (homo): between nonidentical members of same species
xeno (hetero): between members of different species
-graft
-genic
-antigen
-antibody -
thrombocytopenia
type
target
antigen
effect -
type: cytotoxic
target: thrombocytes (platelets)
antigen: aspirin, antibiotics, antihistamine
effect: impaired blood clotting and hemorrhages -
agranulocytosis
type
target
antigen
effect -
type: cytotoxic
target: neutrophils
antigen: drugs
effect: reduced phagocytosis -
goodpasture syndrome
type
target
antigen
effect -
type: cytotoxic
target: kidneys
antigen: own antigens(?)
effect: kidney failure -
myasthenia gravis type
target
antigen
effect -
type: cytotoxic
target: membranes of muscle fibers
antigen: not established
effect: loss of muscle activity -
graves’ disease
type
target
antigen
effect -
type: cytotoxic
target: thyroid gland (hyperactive)
antigen: not established
effect: abundant thyroxine and high metabolic rate -
hashimoto’s disease
type
target
antigen
effect -
type: cytotoxic
target: thyroid gland (hypoactive)
antigen: not established
effect: thyroxine deficiency and low metabolic rate -
serum sickness
type
target
antigen
effect -
type: immune complex
target: kidney
antigen: serum proteins
effect: kidney failure -
arthus phenomenon
type
target
antigen
effect -
type: immune complex
target: blood vessels and site of antigen entry
antigen: environmental antigens
effect: thromboses in blood vessels -
systemic lupus erythematosus
type
target
antigen
effect -
type: immune complex
target: skin, heart, kidney, blood vessels
antigen: own nucleoproteins
effect: butterfly rash, heart, kidney failure -
rheumatoid arthritis
type
target
antigen
effect -
type: immune complex disease
target: joints
antigen: own nucleoproteins
effect: swollen joints