Perio Midterm
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- What is epidemiology?
- Studying the distribution of disease in human populations and the factors that influnce the distribution
- What is (probably) the most successful public health intervention?
- Fluoridation of water to prevent caries
- Why do epidemiological studies matter so much to periodontists?
- Because it is an evidence-based practice
- Define prevalence. How is it calculated?
- The percentage of people in a population who have disease at a given point in time. # of people with the disease / # of people in the population
- Define incidence. How is it calculated?
- The average percentage of unaffected people who will develop disease during a specific period of time, or the measure of how much new disease there is. # of new cases / # of persons at risk when the study began
- Prevalence or incidence: Tells the risk/probability that a person will become a new case.
- Incidence
- Name the two overall types of studies done for prevalence or incidence.
- 1 - Observational 2 - Experimental
- Name the three types of observational studies.
- 1 - Cross-sectional 2- Cohort 3- Case-control
- Most epidemiological studies are (observational/experimental).
- Observational
- Name the most common type of experimental study.
- Drug trials
- What are two synonyms for Cross-sectional studies?
- 1 Disease freqency studies 2 Prevalence studies
- If a cross-sectional study is repeated at regular intervals, what are two advantages?
- 1 Gives information on trends in disease over time 2 Shows effectiveness of prevention/treatment programs
- Name two reasons why cross-sectional studies are better than cohort or case-control studies.
- 1. Cheaper 2. Quicker to conduct
- What does a cohort study reveal about a population?
- Whether an exposure or characteristic is associated with development of disease
- What kind of study starts off with all subjects free of disease?
- Cohort study
- Name 2 disadvantages to cohort studies.
- 1 Requires long observation periods 2 Expensive
- What kind of study starts off with 2 groups; patients with or patients without disease?
- Case-control study
- Name 2 disadvantages to case-control studies.
- 1 Can't determine prevalence 2 Can't determine incidence
- If you want to calculate prevalence, what type of study should you do?
- Cross-sectional study
- If you want to calculate incidence, what type of study should you do?
- Cohort study
- If you want to study association between exposure and disease, what type of study should you do?
- Case-control study
- Sensitivity or Specificity: The percentage of people who have the disease who test positive.
- Sensitivity
- Sensitivity or Specificity: The percentage of people who don't have the disease who test negative.
- Specificity
- Define risk. Define risk factor.
- Risk = The likelihood that a patient will get a disease in a specific time period. Risk factor = Characteristics that place a patient at risk for getting a disease
- What are three ways for exposure to occur?
- 1 Single point in time 2 Episodic 3 Continuous
- If you eliminate a risk factor, does it prevent new disease? Does it get rid of existing disease?
- Prevents - yes. Eliminates - no.
- Name 2 true risk factors for periodontal disease.
- 1 Smoking 2 Diabetes
- Once a patient has periodontal disease, what are two things we must do?
- 1 Reduce risk at healthy sites 2 Increase risk for positive prognosis in diseased sites
- What are 2 different definitions of gingivitis?
- 1 Inflammation on teeth with no attachment loss 2 Inflammation on tooth with healthy, stable, non-progressing attachment loss
- What is gingival index used for?
- It's used to quantify amount and severity of disease in individuals/populations, over time
- What does a gingival index compare: Prevalence or incidence?
- Prevalence
- Name 4 features of an "ideal index".
- 1 Quick to use 2 Accurate 3 Reproducible 4 Quantitative
- Gingival index is (subjective/objective). Gingival bleeding index is (subjective/objective) for diagnosing inflammation.
- Gingival index: Subjective⬦ Gingival bleeding index: objective.
- What happens first in gingiva: bleeding or color change?
- Bleeding always occurs first!
- Describe how you differentiate gingivitis from periodontitis using bleeding index.
- Gingivitis: Drag a perio probe (2 mm) through each sulcus, wait a few seconds, then note bleeding⬦. Periodontitis: Base of pocket, then note bleeding
- What is the direct cause of gingivitis (that all studies have shown)?
- Bacterial plaque
- When and who performed the "classic" experimental gingivitis study?
- 1965 - Loe
- Why have there been no experimental studies on chronic periodontitis?
- Because it is an irreversible destruction of the connective tissue
- Maxillary _________ and mandibular __________ have the most attachment loss of any tooth.
- MOST: Maxillary molars, mandibular incisors
- Maxillary _________ have the least attachment loss of any tooth.
- LEAST: Maxillary incisors
- T/F: Increased pocket depth correlates with age.
- False! It does not!
- Periodontitis becomes clinically significant after age ____.
- 30
- According to the 'new paradigm' for the etiology of periodontitis, what determines the clinical extent and severity of the disease?
- Host inflammatory response
- Smokers are ____ times as likely to develop severe periodontitis than non-smokers.
- 5
- What is the most important host factor for developing periodontitis?
- Cigarette smoking
- What ist he most important predictor for periodontitis?
- Oral hygiene
- Periodontitis is (more severe with/not affected by) the following risk factors: Low socioeconomic/educational status; osteoporosis; HIV/AIDS; infrequent dental visits.
- Low socioeconomic/educational status - more severe; osteoporosis - not affected; HIV/AIDS - not affected; infrequent dental visits - not affected by.
- Periodontitis is (more severe with/not affected by) the following risk factors: bacteria; bleeding on probing; previous periodontal disease; genetic factors; stress.
- bacteria - more severe; bleeding on probing - more severe; previous periodontal disease - more severe; genetic factors - more severe; stress - more severe.
- What is Scaling? What is Root planing?
- Scaling = Removing calculus, food, plaque on enamel AND cementum. Root planing = Removing calculus and contaminated cementum ONLY on root
- With scaling and root planing, the oral flora shifts from Gram (-/+) to Gram (-/+) aerobes.
- From gram - to Gram +
- Name the three classes of bacteria that are bad for oral health.
- 1 Motile rods 2 spirochetes 3 Any black pigmented bacteria
- What researchers' study had 3 periodontists scale/cavitron, and found that deep pockets were affected much more than shallow pockets (even had destroyed periodontal fibers)?
- Sherman
- What were the results of Sherman's study?
- Deeper pockets gained attachment with 3 SRP & Cavitrons, but shallow pockets had no change, or even lost attachment
- What researchers' study compared open (surgical) to closed (non-surgical) treatment and found that in deeper pockets, less calculus was left but there was no difference for shallow pockets?
- Buchanan
- What were the results of Buchanan's study?
- Surgical calculus removal has no affect on pockets less than 6 mm, but there is significant change for deeper pockets when surgical SRP is done
- What very important study compared different SRP techniques on furcations?
- Matia
- What were the results of Matia's study?
- Ultrasonics must be used on furcations because the tip is smaller! Also, surgical is more effective
- How many days does it take, after SRP, to get bacteria to levels of health?
- 3!
- If maintenance of plaque control is absent, it takes __ to ___ weeks to repopulate the pocket with bad bacteria.
- 4-8 weeks
- What researchers' study found that SRP was equally effective as surgical therapy?
- Lindhe and Nyman
- What researchers' study found that at pocket depths greater than 7 mm, there was no difference between surgical and non-surgical treatment?
- Ramfjord
- What researchers' study found that RP, and surgical procedures produced similar gains in pockets greater than 7 mm?
- Kaldahl
- What is substantivity?
- The ability of an agent to bind to tissue surfaces and be released over time
- What item in dentistry has high substantivity?
- Chlorhexidine
- Why are gracey curettes the best for subgingival SRP?
- They provide the best adaptation to root anatomy
- What kind of fulcrum is best for using the Gracey 11-12?
- Extraoral or opposite arch
- Ultrasonics vibrate between __,000 and __,000 cycles/second.
- 20-45,000
- The ideal angle between the face of the blade and the lateral surface of any curette is __ to ___ degrees.
- 70-80
- What is the name of the author who changed her position from 1985 (ultrasonics no good for light treatment) to 1992 (ultrasonics are first choice in treatment of most patients)?
- Irene Woodall
- What is periodontal debridement?
- The mechanical removal of tooth/root surface irritatnts to return to non-inflamed state
- Name 4 basic ways that ultrasonic debridement is accomplished.
- 1 Mechanical 2 Cavitation 3 Irrigation/Submarginal lavage 4 Acoustic turbulence
- What mechanical measurement represents the number of times per second that a tip vibrates back and forth?
- Frequency
- What unit of measurement is used for frequency?
- Kilohertz
- What mechanical measurement represents how great the tip is vibrating side-to-side or round-to-round?
- Tip amplitude
- Frequency or tip amplitude: Can be changed by the power setting on the ultrasonic unit.
- Tip amplitude
- Define cavitation.
- Bursting air bubbles (produced by vibration) cause shock waves in the water, which causes rupture of the cell wall membrane
- What basic component of ultrasonic debridement results in disruption of the bacterial matrix?
- Acoustic turbulence
- How many cps does a sonic instrument use?
- 3-8,000
- Sonic, Magnetostrictive Ultrasonic, or Piezoelectric Ultrasonic: Titan Scaler
- Sonic
- Sonic, Magnetostrictive Ultrasonic, or Piezoelectric Ultrasonic: Micro ICS Scaler
- Sonic
- Sonic, Magnetostrictive Ultrasonic, or Piezoelectric Ultrasonic: Cavitron SPS
- Magnetostrictive Ultrasonic
- Sonic, Magnetostrictive Ultrasonic, or Piezoelectric Ultrasonic: Turbo 25K/30K
- Magnetostrictive Ultrasonic
- Sonic, Magnetostrictive Ultrasonic, or Piezoelectric Ultrasonic: Odontosan
- Magnetostrictive Ultrasonic
- Sonic, Magnetostrictive Ultrasonic, or Piezoelectric Ultrasonic: Piezon Master 400/Mini
- Piezoelectric Ultrasonic
- Sonic, Magnetostrictive Ultrasonic, or Piezoelectric Ultrasonic: P-5 Booster
- Piezoelectric Ultrasonic
- Sonic, Magnetostrictive Ultrasonic, or Piezoelectric Ultrasonic: Pro-Select 3 Scaler/Irrigator
- Piezoelectric Ultrasonic
- How many cps does a magnetostrictive ultrasonic instrument use?
- 25,000-42,000 cps
- How many cps does a piezoelectric ultrasonic instrument use?
- 40,000-50,000 cps
- How does an ultrasonic instrument work?
- Converts electrical energy into mechanical vibrations
- Name the two types of Ultrasonic instruments.
- 1 Magnetostrictive 2 Piezoelectric
- What surfaces of a magnetostrictive ultrasonic are active?
- ALL
- Which functions with an elliptical/orbital motion: Magnetostrictive or piezoelectric?
- Magnetostrictive Ultrasonic
- Which functions with a linear motion: Magnetostrictive or piezoelectric?
- Piezoelectric Ultrasonic
- Which surfaces of a Piezoelectric ultrasonic are active?
- Lateral sides only
- T/F: There is more tactile sense with an ultrasonic scaler.
- False - LESS
- Name 5 medical contraindications to using an ultrasonic scaler.
- 1 Infectious disease 2 Respiratory disease 3 Predisposition to infection 4 Pacemakers 5 Swallowing defects
- Name 3 dental contraindications to using an ultrasonic scaler.
- 1 Sensitivity 2 Areas of demineralization 3 Margins of restorations
- What setting should the water knob on the ultrasonic scaler be set at (%)?
- 80-90%!
- Name three types of strokes that can be used with an ultrasonic scaler.
- 1 Vertical 2 Oblique 3 Circumferential
- Loe's 1965 demonstrated that in the absence of plaque there (was/was no) disease.
- was NO disease
- T/F: Dental plaque bacteria are strongly influenced by environmental factors that may be host mediated.
- TRUE
- What determines periodontal health?
- Balance between bacteria and the host
- Can dental plaque be removed by water squishing into the pockets?
- No, they are adherent to the tooth surface
- Name the two types of bacteria that accumulate at the tooth surface. Name the two types that are found in the outer surface of the mature plaque mass.
- Tooth surface: Gram + Cocci and short rods. Outer surface: Gram - rods and filaments
- Define Long Junctional Epithelium. What is its function?
- It is the migration of the epithelium following SRP. It replaces the lost CT attachment, but is not as good (debatable)
- What did the 1998 Socransky study show about different-colored oral bacteria complexes?
- Red and orange complexes were associated together, and the red complex showed the strongest relationship to periodontal diagnosis.
- Name the three bacteria that made up the "red complex" in the 1998 Socransky study.
- 1 B. Forsythus 2 P.Gingivalis 3 T. Denticola
- In the Brochut study, at six weeks after therapy, the mean total bacterial loads had (no/significant) impact on the bleeding tendency of the subject, six months later.
- SIGNIFICANT
- What did the Brochut study show about the effects of scaling and root planing, which explains why we're required to do 3 OHCs before we can start SRP?
- Perfect oral hygiene is VERY important before non-surgical therapy
- What did the Colombo study show about SRP?
- SRP decreased certain periodontal pathogens, and increased beneficial species for up to 9 months following treatment.
- What did the Haffajee study show about OHC?
- Meticulous removal of suprgingival plaque affects nature of bacteria below and above the gingival margin! (in a good way)
- What did the Fujise study show about P.gingivalis, B.Forsythus, and A.A?
- They are all usefull in assessing treatment outcome!
- What did the Petersilka study demonstrate about intensive subgingival SRP in PPD less than 3 mm?
- This should be avoided, as it will result in AL and traumatize the periodontium.
- What did the Darby study demonstrate about humoral immune response?
- There were no significant post-therapy effects, except reduced antibody avidity to P gingivalis/intermeia (host response may fail to make the antibodies to fight oral flora)
- What did the Cugini studyc conclude about perio maintenance?
- It is essential in maintaining clinical/microbial improvements made by initial treatment.
- What did the Loesche study show about non-invasive treatment?
- It reduced the need for surgery/ext, for at least five years after initial SRP
- Is metronidazole dental gel indicated for an adjunctive treatment for adult periodontitis?
- NO.
- What did the Shiloah study show about microbial pathogens in the oral cavity?
- Their presence negatively affects the outcome of both surgical and non treatment!
- Name the 3 changes in cementum that occur with periodontitis
- 1 Destruction of collagen fibers in cementum 2 Degeneration of Sharpey's fibers 3 NECROSIS of cementum
- What is the one indirect affect of bacteria?
- Their endotoxins prevent attachment of gingival fibroblasts, in vitro
- Name the major etiologic factor of periodontal disease.
- Plaque, especially bacteria that are embedded in the biofilm
- Name the most common endotoxin released by bacteria to disrupt fibroblasts.
- Lipopolysaccharide
- Name 2 proposed mechanisms for hypersensitivity following SRP.
- 1 Hydrodynamic (tubules are exposed) 2 Bacterial sensitization of the pulp
- What is the main goal of removing plaque/calculus?
- Reducing inflammation
- What is the primary goal of SRP treatment itself?
- Reduction of the pocket depth
- In the Experimental Gingivitis study by Loe and Theilade, gingivitis appears after ___ days without plaque control,and returns to gingival health within ___ days after reestablishing oral hygiene.
- 3, 7.
- Name the 4 stages of periodontal disease progression, according to Page and Schroeder.
- 1 Initial lesion 2 Early lesion 3 Established lesion 4 Advanced lesion
- What stage of disease progression is: subclinical, widening of capillaries, and PMN?
- Initial lesion
- What stage of disease progression is: erythematous, and has intensified inflammatory cell response?
- Early lesio n
- What stage of disease progression is: Deeper, bluish colored, has lots of plasma cells, widened intercellular space, destroyed basal lamina/collagen fibers (periodontal tissue destruction)?
- Established lesion
- What stage of disease progression has: extension into alveolar bone?
- Advanced lesion
- __-___ mm of PPD reduction occurs after SRP.
- 2-3 (.5 mm new attachment, 1-.15 junctional epithelium, other from recession of gingiva and decreased inflammation)
- Name the three things that occur with healing after SRP.
- 1 Recession 2 Junctional epithelium attachment 3 New attachment
- Which gingival structure is (basically) impossible to restore if you destroy it during SRP?
- Interdental papilla