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Contaminants (CNTM)

Contaminants (CNTM)

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How do contaminant molds develop into infections?: They are opportunistic; usually 2ndary to another disease in immunocompromised
-due to neutropenia
-due to bad hygiene
How do we seperate the contaminant molds?: Based on microscopic morphology
What are the 5 groups of contaminant molds?: 1. Aseptate hyphae (zygomyc)
2. Septate w/ conidiophore ending in a vesicle
3. Septate w/ conidiophore branching into Penicillus
4. Septate w/ conidia in clusters
5. Septate dematiceous
What are the molds that are aseptate?: Zygomycetes
-Rhizopus
-Mucor
-Absidia
What mold totally resembles zygomcetes but is not?: Syncephalastrum
WHAT IS IT?: Zygomycetes
WHAT IS IT?: aspergilloma
WHAT IS IT?: Aspergillus niger
WHAT IS IT?: Aspergillus fumigatus
WHAT IS IT?: Aspergillus fumigatus
WHAT IS IT?: Syncephalastrum
WHAT IS IT?: Paecilomyces vs. penicillium
WHAT IS IT?: Penicillium
WHAT IS IT?: paecilomyces
WHAT IS IT?: penicillium growth - slightly greenish
WHAT IS IT?: scopulariopsis
WHAT IS IT?: scopulariopsis
WHAT IS IT?: acremonium
WHAT IS IT?: acremonium
WHAT IS IT?: fusarium
WHAT IS IT?: fusarium
WHAT IS IT?: fusarium
WHAT IS IT?: Sepedonium
WHAT IS IT?: Chrysosporium
WHAT IS IT?: chrysosporium
WHAT IS IT?: Gliocladium
WHAT IS IT?: Gliocladium
WHAT IS IT?: Alternaria
WHAT IS IT?: Alternaria
WHAT IS IT?: Alternaria
WHAT IS IT?: curvularia
WHAT IS IT?: curvularia
WHAT IS IT?: drechslera
WHAT IS IT?: cladosporium
WHAT IS IT?: nigrospora
WHAT IS IT?: nigrospora
WHAT IS IT?: ulocladium
WHAT IS IT?: ulocladium
WHAT IS IT?: paecilomyces
What are the 2 molds with Septate hyphae ending in a vesicle?: 1. Aspergillus
2. Syncephalastrum
What are the 4 species of Aspergillus we know of?: 1. A. niger
2. A. fumigatus
3. A. flavus
4. A. glaucus
Which species of aspergillus is most likely to cause a serious systemic infection?: Aspergillus fumigatus
What are 6 diseases caused by aspergillus?: 1. aspergilloma
2. Pulmonary spergillosis
3. Disseminated aspergillosis
4. Otitis externa
5. Keratitis
6. Alergic bronchopulmonary disease
What's another name for allergic bronchopulmonary disease?: Farmer's lung
What are the structures in aspergillus?: -Septate hyphae
-Conidiophore, terminates in a vesicle
-Phialides -> phialoconidia in chains
What are the structures in Syncephalastrum?: -Aseptate hyphae
-Sporangiophore, terminates in a vesicle
-Sporangiospores in chains come off vesicle
-Mesosporangia contains the chains of spores
What is common to both penicillium and paecilomyces?: Fingerlike spreading of phialides bearing phialoconidia
What is different between penicillium/paecilomyces?: -Elongated phialides in paecilomyces.
-ROUND phialoconidia in penicillium.
What species of penicillium is commonly seen in labs?: Penicillium marneffei
What colonial colors are: -Penicillium -Paecilomyces: Penicillium = white -> green
Paecilomycs = white -> tanner
What 5 molds have aseptate hyphae w/ conidia clustered?: 1. Acremonium
2. Fusarium
3. Sepedonium
4. Chysosporium
5. Gliocladium
What does sepedonium resemble?: H. capsulatum (budding conidia)
What are characteriscts of Chyrsosporium?: Clavate, aseptate hyphae, intercalcary
What are the 6 demataceous fungi with septate hyphae?: CADCUN
Curvularia, alternaria, drechslera, cladosporium, ulocladium, nigrospora.
At maturity what colors are: A. niger A. fumigatus A. flavus A. glaucus: Niger = black
Fumigatus/flavus = dark green
Glaucus = yellow-brown
Which aspergillus has unique conidiophore, and what is it?: Aspergillus flavus; rough, echinulate conidiophore
which aspergillus species have double phialides? How are they arranged around ves?: Niger/flavus; cover entire vesicle and radiate OUT.
What type of vesicles does a. fumigatus have?: Single; cover upper 1/3 to 2/3 of vesicle and stick UP.
What type of vesicles does a. glaucus have?: Single; loosely arranged and radiate out.
Which aspergillus has cleistotheicia?: A. glaucus.

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