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Anatomy Chapter 10

Terms

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Sarco-
Muscle
Sliding filament theory (4 steps)
1) Action potential causes depolarization and release of calcium from the SR, 2) Calcium diffuses across and binds to troponin to move tropomyosin to allow binding of myosin head to binding sites, 3) Myosin head pivots to pull thin filament, need ATP instead of ATD for myosin head to let go. 4) Calcium actively taken back into SR and the muscle relaxes
Functions of skeletal muscle
Movement, posture/position, supports soft tissues, guards entrances and exits (eyes, mouth, anus), temperature (use ATP for muscle contraction. 40% of energy is usable, 60% is given off as heat)
Surrounds fascicle
Perimysium
3 Types of muscle
Smooth, cardiac, and skeletal. All 3 designed to contract
Z-lines
Thin filament (thin horizontal lines), Thick filament (darker horizonal lines). From one z-line to another is one sarcomere
Power Stroke
Pull thin filament across thick filament
Sarcomere
Functional unit of muscle where the contraction takes place
Sarcomere composition
Thick filament made of myosin (two subunits twisted around each other with 2 tails and 2 heads.) M-line is where the tails come together
Cross Bridge
Created when myosin heads bind to active actin sites
Wrap around the sarcoplasmic reticulum
T-Tubules
Surrounds bundles of myofibril protein fibers
Sarcoplasmic reticulum
Thin filament proteins
Actin (2 twisted chains of globular molecules), tropomyosin (blocks myosin binding sites), troponin (moves tropomyosin)
Causes contraction in muscle
Must move away tropomyosin from the binding site to allow binding. Control using calcium
Cell membrane in muscle cell
Sarcolemma
Center of sarcomere
M-line
Skeletal muscle tissue
Striated, mostly voluntary (respiratory is involuntary), multinucleate (more than one nucleus) so lots of DNA to code for protein synthesis, tendon attaches muscle to bone
2 primary proteins in muscle
Actin and Myosin
Long pores in sarcolemma
T-Tubules (transverse tubules)
Group of muscle cells
Muscle fascicle
Surrounds entire muscle
Epimysium
Surrounds muscle filbers
Endomysium

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