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ANA 16

Terms

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acquired immunodeficiency syndrome (AIDS)
aquired condition that impairs the body's ability to fight disease; it is the end stage of continuum of HIV infection.
HIV disease
is a broad diagnostic term that includes the pathology and clinical illness caused by HIV infection.
vertical transmission
of HIV or transmission from mother to fetus, can occur during pregnancy, delivery, or through postpartum breastfeeding - in milk.
HIV is a obligate virus...which means what?
it must have a host organism to survive
HIV carries its genetic material how?
in RNA rather than DNA....and it replicates by converting RNA to DNA
Perinatal transmission
HIV can be transmitted from mother to the infant during pregnancy, at time of delivery, or after birth....thru breast feeding
VERTICAL TRANSMISSION IS?
TRANSMISSION OF HIV FROM MOTHER TO CHILD
seroconversion
the process after exposure to a disease in which the blood changes from negative to positive ( after having a ELISA test)
phagocytic
ingestion and digestion of bacteria ingestion. Infected monocytes move into the body tissues, were the differentiate into macrophages.
human immunodeficiency virus( HIV)
a retro-virus that causes HIV infection and HIV disease ( AKA )zoonotic- crossed from zoo animal species over to humans.
HAART = ?
HIGHLY ACTIVE ANTIRETROVIRAL THERAPY
percutaneous exposure w/ aids is defined as?
a needlestick exposure to known HIV-infected blood
viral load
or burden refers to a quantitative measure of HIV viral RNA in the peripheral circulation....the higher the load the worse the condition is
what R most common modes of transport for HIV?
anal, vaginal,contaminated needles/paraphernalia, & trans from mother to child
retrovirus
viruses the contain RNA as their genetic information; making DNA from RNA
CD4 CELL MONITORING...
IS 1 OF LAB PARAMETERS USED TO TRACK THE PROGRESSION OF HIV DISEASE, if there is decrease in CD4 the more severe the immunosuppression becomes
viral load
amount of measurable HIV virons is highest immediately after injection and during the later stages of the disease.
opportunistic
caused by normally nonpathogenic organisms in a host whose resistance has been decreased by such disorders as HIV disease.
SYMPTOMATIC HIV DISEASE
HIV infection may exist for amny years w/o symptoms...before it progresses to this..........(symptomatic)....unexplained fever, night sweats, diarrhea, weight loss and fatigue
pneumocystis jiroveci ( formerly carinii) pneumonia (PCP)
an unusual pulmonary disease caused by a fungus and primarily associated /c people who have suppressed immune systems ( cases were noticed by Dr's in NY and CA)
what are the 2 phases of HIV
asymptomatic & symptomatic
HIV disease is Dx'ed when?
the CD4 cell count is 200cell/mm3 or fewer
marker for antibodies are usually present in 10-12 weeks after exposure....
seroconversion
virulent
dangerous; harmful, toxic Extremely infectious, harmful, or poisonous, as a disease or toxin.
HIV disease results from progressive deterioration of immune system over time....when is AIDS Dx'ed?
AIDS is made in a later stage of this progression, it is the end stage of the continuum of HIV infection
HOW SOON WILL ANTIBODIES SHOW IN BLOOD AFTER UNSAFE SEX?
4-12 WEEKS
education on prevention is the only truly effective "vaccine" available to curb the HIV pandemic
true
seronegative
test doesn't mean the the individual is free from the risk of infection
what is 1 of the most common infections seen w/ early symptomatic disease is?
ORAL CANDIDIASIS(thrush) whitish, curdlike substance on the tongue inside the mouth, SHINGLES IS ANOTHER AND PERSISTENT VAGINAL CANDIDIASIS...(YEAST INFECTIONS)
seroconversion...is what?
is devel. of antibodies from HIV...takes place 5 days to 3 mos. after exposure....generally w/in 1-3 weeks, most pep's the acute retroviral illness is mild and may B mistaken fro a cold or minor viral infeftion
adherence
the maintenance of adherence to prescribe regimen os of paramount importance to survival and the success of the treatment.
kaposi's sarcoma
a rare cancer of the skin and mucous membranes characterized by blue,red, or purple raised lesions seen mainly in Mediterranean men
ZOONOTIC
HIV is known as this......organism that has been abler to cross from an animal species to humans
CD4+ counts are important markers of disease progression and the status of what?
the immune system
center for disease control and prevention (CDC)
a division of the U.S. public health service in Atlanta Georgia, that investigates and controls various diseases, especially those that have epidemic potential.
CD4+ lymphocyte
plays a pivotal role in the ability of the immune system to recognize and defend against foreign invaders. (adults normally have 600-1200 CD4 lymphocytes per microliter of blood)
enzyme-linked immunosorbent assay (ELISA)
a rapid enzyme immunochemical assay method to detect certain bacterial antigens and antibodies.
WHAT IS ADJUNCTIVE ACTIVITIES?
MASSAGE, ACUPUNCTURE, ACUPRESSURE, & BIOFEEDBACK
HIV disease/AIDS is Dx'ed accord. to what?
CD4 counts
Antiretrovial Therapy
I think these are the "cocktails" for Pt's w/ HIV
when an HIV Pt is taking drugs what is one of the important things for that person to follow?
Pt must maintain vigilance with their treatment. (always taking their drugs at specific times...if they miss they help to create drug risistance
excoriation
a strong denunciation; the act or state of stripping or wearing off the skin....this can happen in the perianal area
HIV infection
the state in which HIV enters the body under favorable conditions and multiplies, producing injurious effects.
immune dysfunction results predominantly from what?
dysregulation & destruction of T-helper cells, or CD4+ lymphocytes, these DC4 and lymphocytes play pivotal role in ability of immune system to recognize and defend against foreign invaders
THE HIV FACTORY IN THE HUMAN BODY IS?
INFECTED CD4 CELLS

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