Cleft Lip
Terms
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- What is the incidence of CL/CLP in whites?
- 1 in 750
- What is the incidence of CL/CLP in asian?
- 1 in 500
- What is the incidence of CL/CLP in black?
- 1 in 2000
- What is the ratio of left to right to bilateral clefts
- 6:3:1
- what is the ratio of CLP to CL?
- 2:1
- What is the risk of having a child with CLP if the parents have 1 child with CLP?
- 4%
- What is the risk of having a child with CLP if one parent has CLP?
- 2% to 4%
- What is the risk of having a child with CLP if the parents have 2 child with CLP?
- 9%
- What is the risk of having a child with CLP if one child and one parent have CLP?
- 14% to 17%
- What is the normal vertical length of the upper lip in a newborn, age 3 months, and adult?
- 10mm,13mm, 17mm
- What syndromes are associated with CLP/CL?
- Van der woude, waardendurg' syndrome, down syndrome, trisomy 13, stickler's syndrome, Pierre Robin sequence, velocardiofacial syndrome and median cleft lip
- What is the inheritance pattern of Van der Woude's syndrome?
- Autosomal Dominant
- What are the associated findings in Van der Woude's syndrome?
- lip pits, absent second molars, syndactyly, adnormal genitalia, and popliteal pterygia
- What is the cause of waardenburg syndrome?
- abnormal development and migration of neural crest cells
- What is the inhertiance pattern of Stickler's syndrome?
- Autosomal dominant
- What are the typical features of Stickler's syndrome?
- CP, progressive joint degeneration, ocular abnormalities leading to blindness
- what is the rule of tens?
- 10 weeks, weight 10 pounds, and have a hemoglobin of at least 10 mg/dl