C. dipth, A. haem, M. catt, Entero, Mycopl
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- Elicits immune response that causes tough, adherent PSEUDOMEMBRANE formation in throat
- Corynebacterium diphtheriae
-
"Name agent for following Diagnostic proc A. Tellurite plate
grows black colonies B. Selective medium culture
-poor growth on tellurite C. ""Fried eggs"" on culture " -
"A. C. diphtheriae
B. Arcanobacterium Haemolyticum
C. Mycoplasma pneumoniae" - Underdiagnosed cause of PHARYNGITIS in older children and young adults
- Arcanobacterium haemolyticum
-
"Virulence Factors
A. Exotoxin that inhibits protein synthesis by binding adding ADP ribose to EF-2
B. Protein P1: adheres to epithelium of respiratory tract
C. Produces DNAase enzymes and butyrate esterase " -
"A. Corynebacterium diphtheriae
B. Mycoplasma pneumoniae
C. Moraxella Catarrhalis" - T/F: Mycoplasma pneumoniae stains purple on gram stain
- FALSE: Mycoplasma pneumoniae has NO CELL WALL --->NO GRAM STAIN
- Arcanobacterium haemolyticum is a close relative of ________?
- Corynebacterium (used to be called Corynebacterium haemolyticum)
- T/F: A domain of Diphtheriae AB toxin binds to cell surface receptors
-
"FALSE: ""A domain is catalytic and Adds ADP ribose to EF-2.
B domain Binds to cell surface receptors" - Name the members of the family Enterobateriaceae
-
"E. coli
Pseudomonas
Burkholderia
Proteus mirabilis
Providencia
Serratia
Enterobacteria
""Serratia BurPs ProtEin in Providence and got /E. Coli""
(BurPs= Burkholderia and Pseudomonas
ProtEin= Proteus and Enterobacteria
Providence= Providencia)" - A. Aerobic, gram - rod common in soil and moist environments (water, hospital respirators, humidifers)
- A. Burkholderia Cepacia
- B. Aerobic, non-lactose fermenting gram -rod which is OXIDASE positive (differentiates it from other members of the Enterobacteriaceae family)
- B. Pseudomonas Aeruginosa
- Which of these is not part of the normal flora in humans? Serratia Marscecens, Moraxella Catarrhalis, Arcanobacterium haemolyticum
- Arcanobacterium haemolyticum
- T/F: Pencillin G is an effective treatment for Pseudomonas aeruginosa
- FALSE: P. aeruginosa is NATURALLY RESISTANT to a variety of antibiotics **little pre-pharm pearl: use Piperacillin/ Ticarcillin to treat (B-lactam derivatives of penicillin)***
-
"Name agent for each associated dz
A. ""Cepacia"" syndrome and Fulminant pneumonia
B. Atypical Walking Pneumonia
C. Bullous Myringitis
D. ""Bull neck"" lymphadenopathy
E. Pharyngitis a -
"A. Burkolderia cepacia
B. Mycoplasma pneumoniae
C. Mycoplasma pneumoniae
D. Corynebacterium diphtheriae
E. Arcanobacterium haemolyticum
F. Enterobacteriaceae" - What two agents are the leading causes of pneumonia and UTIs in cystic fibrosis patients?
- PSEUDOMONAS AERUGINOSA and BURKHOLDERIA CEPACIA
-
"Name agent for each vaccine
A. LOS (lipoligosaccharide) vaccine under development)
B. Inactivated toxoid vaccine usu given in combination with tetanus toxid and pertussis vaccine" -
"A. Morexella Catarrhalis
B. Corynebacterium diphtheriae" -
"Name agent and the COLOR of the gram stain that you would see
A. Club-shaped rod in V or L formations that look like Chinese characters; METHYLENE BLUE reveals granules
B. ""Coryneform/diphtheriod"" rod that is a Facul -
"A. Corynebacterium diphtheriae; PURPLE (GRAM +)
B. Arcanobacterium Haemolyticum; PURPLE (GRAM +)
C. Moraxella catarrhalis: PINK
(GRAM -)
D. Burkholderia cepacia; PINK
(GRAM -)
E. Mycoplasma pneumoniae; NO GRAM STAIN!! ;-)" - The DNA of this organism is part of a bacteriphage (virus!) that integrates it into bacterial chromosome and synthesizes an exotoxin
-
"Corynebacterium diphtheriae
(toxin = AB toxin)" - How would you treat a patient suffering from flu-like symptoms, toxic appearance, painful pharyngitis, and pronounced "bull neck" lymphadenopathy?
-
"DIPTHERIA!!
Immediately give ANTITOXIN that neutralizes unbound toxin in blood
Hospitalize and Isolate patient
Give Erythromycin (Antibiotic) to kill bacteria
***20% mortality if untreated**" - How would you treat a patient suffering mild PHARYNGITIS and cervical lymphadenopathy, and has virus-like symptoms?
-
"Patient infected with Arcanobacterium haemolyticum
Give Erythromycin (Antibiotocs)
***readily treatable***" -
"Name the agent for the following dz:
A. Third leading cause of ACUTE SINUSITIS
B. Laryngeal nerve palsy
C. Fulminant pneumonia with symptoms similar to pseudomonas
D. Community-acquired pneumonia common in younger patients (10-1 -
"A. Moraxella catarrhalis
B. Corynebacterium diphtheriae
C. Burkholderia cepacia
D. Mycoplasma pneumoniae" - T/F: Penicillins and Cephalosporins effectively treat M. pneumoniae
- FALSE: Mycoplasma pneumoniae has no cell wall, so B-lactams and cephalosporins, which inhibit cell wall synthesis, are ineffective
-
"A. Aerobic, Non-spore forming gram + rod with metachromatic-staining granules
B. Enteric, gram - rod similar to Klebsiella pneumoniae; forms red-pigmented colonies
C. smallest bacteria capable of growth and reproduction outside a cell; re -
"A. Corynebacterium diphtheriae
B. Serratia marcescens
C. Mycoplasma pneumoniae" - T/F: E. Coli, a gram - rod, produces an exotoxin that can cause septic shock, bloody diarrhea, and UTIs
- FALSE: E. coli is gram (-) enterobacteriacae; therefore produces ENDOTOXIN that causes sepsis and ENTEROTOXINS that cause diarrhea; UTIs are caused when E. coli ascends into urethra
- Higly motile gram - rod that produces UREASE and is Indole +.
- Providencia rettgeri
- T/F: Members of the family Enterobacteriacae are major causes of Urinary Tract Infections and sepsis
- TRUE
- T/F: Conjuctivitis, keratitis, and bronchopneumonia are 3 pathologies associated with Moraxella Catarrhalis
- TRUE